Amphipathic DNA polymers exhibit antiviral activity against systemic Murine Cytomegalovirus infection

BACKGROUND: Phosphorothioated oligonucleotides (PS-ONs) have a sequence-independent, broad spectrum antiviral activity as amphipathic polymers (APs) and exhibit potent in vitro antiviral activity against a broad spectrum of herpesviruses: HSV-1, HSV-2, HCMV, VZV, EBV, and HHV-6A/B, and in vivo activ...

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Detalhes bibliográficos
Main Authors: Cardin, Rhonda D, Bravo, Fernando J, Sewell, Andrea P, Cummins, James, Flamand, Louis, Juteau, Jean-Marc, Bernstein, David I, Vaillant, Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2794273/
https://ncbi.nlm.nih.gov/pubmed/19954538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-6-214
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