Amphipathic DNA polymers exhibit antiviral activity against systemic Murine Cytomegalovirus infection

BACKGROUND: Phosphorothioated oligonucleotides (PS-ONs) have a sequence-independent, broad spectrum antiviral activity as amphipathic polymers (APs) and exhibit potent in vitro antiviral activity against a broad spectrum of herpesviruses: HSV-1, HSV-2, HCMV, VZV, EBV, and HHV-6A/B, and in vivo activ...

Full description

Saved in:
Bibliographic Details
Main Authors: Cardin, Rhonda D, Bravo, Fernando J, Sewell, Andrea P, Cummins, James, Flamand, Louis, Juteau, Jean-Marc, Bernstein, David I, Vaillant, Andrew
Format: Artigo
Language:Inglês
Published: BioMed Central 2009
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2794273/
https://ncbi.nlm.nih.gov/pubmed/19954538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-6-214
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items