Phosphorothioate Oligonucleotides Inhibit Human Immunodeficiency Virus Type 1 Fusion by Blocking gp41 Core Formation

Several studies have shown that phosphorothioate oligodeoxynucleotides (PS-ONs) have a sequence-independent antiviral activity against human immunodeficiency virus type 1 (HIV-1). It has also been suggested that PS-ONs inhibit HIV-1 by acting as attachment inhibitors that bind to the V3 loop of gp12...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Vaillant, Andrew, Juteau, Jean-Marc, Lu, Hong, Liu, Shuwen, Lackman-Smith, Carol, Ptak, Roger, Jiang, Shibo
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2006
Sujets:
Antiviral Agents
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1426958/
https://ncbi.nlm.nih.gov/pubmed/16569857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.50.4.1393-1401.2006
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