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Potent Antiscrapie Activities of Degenerate Phosphorothioate Oligonucleotides
Although transmissible spongiform encephalopathies (TSEs) are incurable, a key therapeutic approach is prevention of conversion of the normal, protease-sensitive form of prion protein (PrP-sen) to the disease-specific protease-resistant form of prion protein (PrP-res). Here degenerate phosphorothioa...
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| Hauptverfasser: | , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology
2006
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1426446/ https://ncbi.nlm.nih.gov/pubmed/16495266 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.50.3.1034-1044.2006 |
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