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A Porphyrin Increases Survival Time of Mice after Intracerebral Prion Infection

Prion diseases, including scrapie, are incurable neurodegenerative disorders. Some compounds can delay disease after a peripheral scrapie inoculation, but few are effective against advanced disease. Here, we tested multiple related porphyrins, but only Fe(III)meso-tetra(4-sulfonatophenyl)porphine in...

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Auteurs principaux: Kocisko, David A., Caughey, Winslow S., Race, Richard E., Roper, Grant, Caughey, Byron, Morrey, John D.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2006
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1366918/
https://ncbi.nlm.nih.gov/pubmed/16436739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.50.2.759-761.2006
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