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Mefloquine, an Antimalaria Drug with Antiprion Activity In Vitro, Lacks Activity In Vivo

In view of the effectiveness of antimalaria drugs inhibiting abnormal protease-resistant prion protein (PrP-res) formation in scrapie agent-infected cells, we tested other antimalarial compounds for similar activity. Mefloquine (MF), a quinoline antimalaria drug, was the most active compound tested...

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Detaylı Bibliyografya
Asıl Yazarlar: Kocisko, David A., Caughey, Byron
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2006
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1346870/
https://ncbi.nlm.nih.gov/pubmed/16379006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.2.1044-1046.2006
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