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Mefloquine, an Antimalaria Drug with Antiprion Activity In Vitro, Lacks Activity In Vivo
In view of the effectiveness of antimalaria drugs inhibiting abnormal protease-resistant prion protein (PrP-res) formation in scrapie agent-infected cells, we tested other antimalarial compounds for similar activity. Mefloquine (MF), a quinoline antimalaria drug, was the most active compound tested...
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| Hlavní autoři: | , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Microbiology
2006
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1346870/ https://ncbi.nlm.nih.gov/pubmed/16379006 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.2.1044-1046.2006 |
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