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Cyclic Tetrapyrrole Sulfonation, Metals, and Oligomerization in Antiprion Activity
Cyclic tetrapyrroles are among the most potent compounds with activity against transmissible spongiform encephalopathies (TSEs; or prion diseases). Here the effects of differential sulfonation and metal binding to cyclic tetrapyrroles were investigated. Their potencies in inhibiting disease-associat...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society for Microbiology (ASM)
2007
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2151414/ https://ncbi.nlm.nih.gov/pubmed/17709470 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01599-06 |
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