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Nucleic Acid Polymers Are Active against Hepatitis Delta Virus Infection In Vitro

In this study, an in vitro infection model for the hepatitis delta virus (HDV) was used to evaluate the antiviral effects of phosphorothioate nucleic acid polymers (NAPs) and investigate their mechanism of action. The results show that NAPs inhibit HDV infection at concentrations less than 4 μM in c...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Beilstein, Frauke, Blanchet, Matthieu, Vaillant, Andrew, Sureau, Camille
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5790928/
https://ncbi.nlm.nih.gov/pubmed/29212929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01416-17
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