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Nucleic Acid Polymers Are Active against Hepatitis Delta Virus Infection In Vitro

In this study, an in vitro infection model for the hepatitis delta virus (HDV) was used to evaluate the antiviral effects of phosphorothioate nucleic acid polymers (NAPs) and investigate their mechanism of action. The results show that NAPs inhibit HDV infection at concentrations less than 4 μM in c...

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Publicat a:J Virol
Autors principals: Beilstein, Frauke, Blanchet, Matthieu, Vaillant, Andrew, Sureau, Camille
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5790928/
https://ncbi.nlm.nih.gov/pubmed/29212929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01416-17
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