Nitric oxide-induced genotoxicity, mitochondrial damage, and apoptosis in human lymphoblastoid cells expressing wild-type and mutant p53

Por Li, Chun-Qi, Trudel, Laura J., Wogan, Gerald N.
Publicado em 2002

Endogenously produced nitric oxide mitigates sensitivity of melanoma cells to cisplatin

Por Godoy, Luiz C., Anderson, Chase T. M., Chowdhury, Rajdeep, Trudel, Laura J., Wogan, Gerald N.
Publicado em 2012

Delivery method, target gene structure and growth properties of target cells impact mutagenic responses to reactive nitrogen and oxygen species

Por Young Kim, Min, Hoon Lim, Chang, Trudel, Laura J., Deen, William M., Wogan, Gerald N.
Publicado em 2012

Nitric oxide produced endogenously is responsible for hypoxia-induced HIF-1α stabilization in colon carcinoma cells

Por Chowdhury, Rajdeep, Godoy, Luiz C., Thiantanawat, Apinya, Trudel, Laura J., Deen, William M., Wogan, Gerald N.
Publicado em 2012

Nitric oxide activation of Keap1/Nrf2 signaling in human colon carcinoma cells

Por Li, Chun-Qi, Kim, Min Young, Godoy, Luiz C., Thiantanawat, Apinya, Trudel, Laura J., Wogan, Gerald N.
Publicado em 2009

Threshold Effects of Nitric Oxide-Induced Toxicity and Cellular Responses in Wild-type and p53-Null Human Lymphoblastoid Cells

Por Li, Chun-Qi, Pang, Bo, Kiziltepe, Tanyel, Trudel, Laura J., Engelward, Bevin P., Dedon, Peter C., Wogan, Gerald N.
Publicado em 2006

A system for exposing molecules and cells to biologically relevant and accurately controlled steady-state concentrations of nitric oxide and oxygen

Por Dendroulakis, Vasileios, Russell, Brandon S., Elmquist, C. Eric, Trudel, Laura J., Wogan, Gerald N., Deen, William M., Dedon, Peter C.
Publicado em 2012

Reactive nitrogen species regulate autophagy through ATM-AMPK-TSC2–mediated suppression of mTORC1

Por Tripathi, Durga N., Chowdhury, Rajdeep, Trudel, Laura J., Tee, Andrew R., Slack, Rebecca S., Walker, Cheryl Lyn, Wogan, Gerald N.
Publicado em 2013

AFB(1)-induced mutagenesis of the gpt gene in AS52 cells

Por Wattanawaraporn, Roongtiwa, Kim, Min Young, Adams, Jillian, Trudel, Laura J., Woo, Leslie L., Croy, Robert G., Essigmann, John M., Wogan, Gerald N.
Publicado em 2012

Intracellular Generation of ROS by 3,5-Dimethylaminophenol: Persistence, Cellular Response, and Impact of Molecular Toxicity

Por Chao, Ming-Wei, Erkekoglu, Pinar, Tseng, Chia-Yi, Ye, Wenjie, Trudel, Laura J., Skipper, Paul L., Tannenbaum, Steven R., Wogan, Gerald N.
Publicado no Toxicol Sci (2014)

Increased levels of inosine in a mouse model of inflammation

Por Prestwich, Erin G, Mangerich, Aswin, Pang, Bo, McFaline, Jose L, Lonkar, Pallavi, Sullivan, Matthew R, Trudel, Laura J, Taghizedeh, Koli, Dedon, Peter C
Publicado em 2013

Aflatoxin B(1)-DNA Adduct Formation and Mutagenicity in Livers of Neonatal Male and Female B6C3F1 Mice

Por Woo, Leslie L., Egner, Patricia A., Belanger, Crystal L., Wattanawaraporn, Roongtiwa, Trudel, Laura J., Croy, Robert G., Groopman, John D., Essigmann, John M., Wogan, Gerald N.
Publicado em 2011

Genotoxicity of 2,6- and 3,5-Dimethylaniline in Cultured Mammalian Cells: The Role of Reactive Oxygen Species

Por Chao, Ming-Wei, Kim, Min Young, Ye, Wenjie, Ge, Jing, Trudel, Laura J., Belanger, Crystal L., Skipper, Paul L., Engelward, Bevin P., Tannenbaum, Steven R., Wogan, Gerald N.
Publicado em 2012

A Single Neonatal Exposure to Aflatoxin B(1) Induces Prolonged Genetic Damage in Two Loci of Mouse Liver

Por Wattanawaraporn, Roongtiwa, Woo, Leslie L., Belanger, Crystal, Chang, Shiou-chi, Adams, Jillian E., Trudel, Laura J., Bouhenguel, Jason T., Egner, Patricia A., Groopman, John D., Croy, Robert G., Essigmann, John M., Wogan, Gerald N.
Publicado em 2012

In Vivo Biosensing Via Tissue Localizable Near Infrared Fluorescent Single Walled Carbon Nanotubes

Por Iverson, Nicole M, Barone, Paul W, Shandell, Mia, Trudel, Laura J, Sen, Selda, Sen, Fatih, Ivanov, Vsevolod, Atolia, Esha, Farias, Edgardo, McNicholas, Thomas P, Reuel, Nigel, Parry, Nicola M. A., Wogan, Gerald N, Strano, Michael S
Publicado em 2013

Increased p53 mutation load in nontumorous human liver of Wilson disease and hemochromatosis: Oxyradical overload diseases

Por Hussain, S. Perwez, Raja, Kamran, Amstad, Paul A., Sawyer, Mark, Trudel, Laura J., Wogan, Gerald N., Hofseth, Lorne J., Shields, Peter G., Billiar, Timothy R., Trautwein, Christian, Höhler, Thomas, Galle, Peter R., Phillips, David H., Markin, Rodney, Marrogi, Aizen J., Harris, Curtis C.
Publicado em 2000

JS-K, a GST-activated nitric oxide generator, induces DNA double-strand breaks, activates DNA damage response pathways, and induces apoptosis in vitro and in vivo in human multiple...

Por Kiziltepe, Tanyel, Hideshima, Teru, Ishitsuka, Kenji, Ocio, Enrique M., Raje, Noopur, Catley, Laurence, Li, Chun-Qi, Trudel, Laura J., Yasui, Hiroshi, Vallet, Sonia, Kutok, Jeffery L., Chauhan, Dharminder, Mitsiades, Constantine S., Saavedra, Joseph E., Wogan, Gerald N., Keefer, Larry K., Shami, Paul J., Anderson, Kenneth C.
Publicado em 2007