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Delivery method, target gene structure and growth properties of target cells impact mutagenic responses to reactive nitrogen and oxygen species

Dysregulated production of nitric oxide (NO(•)) and reactive oxygen species (ROS) by inflammatory cells in vivo may contribute to mutagenesis and carcinogenesis. Here we compare cytotoxicity and mutagenicity induced by NO(•) and ROS in TK6 and AS52 cells, delivered by two methods: a well-characteriz...

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Hlavní autoři: Young Kim, Min, Hoon Lim, Chang, Trudel, Laura J., Deen, William M., Wogan, Gerald N.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3328651/
https://ncbi.nlm.nih.gov/pubmed/22303861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx2004882
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