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A Single Neonatal Exposure to Aflatoxin B(1) Induces Prolonged Genetic Damage in Two Loci of Mouse Liver
Aflatoxin B (1) (AFB(1)) is a risk factor for hepatocellular carcinoma in humans. Infant, but not adult, mice are sensitive to AFB(1)-induced liver carcinogenesis; a single dose during the neonatal period leads to hepatocellular carcinoma in adulthood. Earlier work defined the mutational spectrum in...
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Main Authors: | , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3493187/ https://ncbi.nlm.nih.gov/pubmed/22539618 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfs151 |
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