Sulforaphane-Mediated Reduction of Aflatoxin B(1)-N(7)-Guanine in Rat Liver DNA: Impacts of Strain and Sex

Aflatoxin B(1) (AFB(1)) is a DNA-binding toxin that contributes to the burden of liver cancer in tropical areas. AFB(1)-DNA adducts are powerful biomarkers that discern individual and population risk from exposure to this carcinogen. The discovery of concordance between the metabolic pathways of the...

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Hlavní autoři: Fiala, Jeannette L. A., Egner, Patricia A., Wiriyachan, Nirachara, Ruchirawat, Mathuros, Kensler, Kevin H., Wogan, Gerald N., Groopman, John D., Croy, Robert G., Essigmann, John M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2011
Témata:
Carcinogenicity
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3080186/
https://ncbi.nlm.nih.gov/pubmed/21278056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfr026
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