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Prenatal exposure of mice to the human liver carcinogen Aflatoxin B(1) reveals a critical window of susceptibility to genetic change

It has become axiomatic that critical windows of susceptibility to genotoxins exist and that genetic damage in utero may be a trigger for later life cancers. Data supporting this critical window hypothesis are remarkably few. This study provides a quantitative bridge between DNA damage by the liver...

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Detalhes bibliográficos
Publicado no:Int J Cancer
Main Authors: Chawanthayatham, Supawadee, Thiantanawat, Apinya, Egner, Patricia A., Groopman, John D., Wogan, Gerald N., Croy, Robert G., Essigmann, John M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4289428/
https://ncbi.nlm.nih.gov/pubmed/25070670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.29102
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