Nitric oxide activation of Keap1/Nrf2 signaling in human colon carcinoma cells

The transcription factor NF-E2-related nuclear factor 2 (Nrf2) regulates expression of genes that protect cells from oxidative damage. Here, we characterized nitric oxide (•NO)-induced Nrf2–Kelch-like ECH-associated protein 1 (Keap1) signaling and its role in counteracting •NO-induced apoptosis of h...

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Hlavní autoři: Li, Chun-Qi, Kim, Min Young, Godoy, Luiz C., Thiantanawat, Apinya, Trudel, Laura J., Wogan, Gerald N.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2009
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2732862/
https://ncbi.nlm.nih.gov/pubmed/19706542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0907539106
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