Autophagy promotes escape from phosphatidylinositol 3-kinase inhibition in estrogen receptor–positive breast cancer

av Yang, Wei, Hosford, Sarah R., Traphagen, Nicole A., Shee, Kevin, Demidenko, Eugene, Liu, Stephanie, Miller, Todd W.
I publikationen FASEB J (2018)

Estrogen receptor alpha drives mTORC1 inhibitor-induced feedback activation of PI3K/AKT in ER+ breast cancer

av Yang, Wei, Schwartz, Gary N., Marotti, Jonathan D., Chen, Vivian, Traphagen, Nicole A., Gui, Jiang, Miller, Todd W.
I publikationen Oncotarget (2018)

High estrogen receptor alpha activation confers resistance to estrogen deprivation and is required for therapeutic response to estrogen in breast cancer

av Traphagen, Nicole A., Hosford, Sarah R., Jiang, Amanda, Marotti, Jonathan D., Brauer, Brooke L., Demidenko, Eugene, Miller, Todd W.
I publikationen Oncogene (2021)

Estrogen therapy induces an unfolded protein response to drive cell death in ER+ breast cancer

av Hosford, Sarah R., Shee, Kevin, Wells, Jason D., Traphagen, Nicole A., Fields, Jennifer L., Hampsch, Riley A., Kettenbach, Arminja N., Demidenko, Eugene, Miller, Todd W.
I publikationen Mol Oncol (2019)

Cytokine sensitivity screening highlights BMP4 pathway signaling as a therapeutic opportunity in ER(+) breast cancer

av Shee, Kevin, Jiang, Amanda, Varn, Frederick S., Liu, Stephanie, Traphagen, Nicole A., Owens, Philip, Ma, Cynthia X., Hoog, Jeremy, Cheng, Chao, Golub, Todd R., Straussman, Ravid, Miller, Todd W.
I publikationen FASEB J (2019)

Exploiting mitochondrial and metabolic homeostasis as a vulnerability in NF1 deficient cells

av Allaway, Robert J., Wood, Matthew D., Downey, Sondra L., Bouley, Stephanie J., Traphagen, Nicole A., Wells, Jason D., Batra, Jaya, Melancon, Sir Norman, Ringelberg, Carol, Seibel, William, Ratner, Nancy, Sanchez, Yolanda
I publikationen Oncotarget (2017)

Tumor pharmacokinetics and pharmacodynamics of the CDK4/6 inhibitor ribociclib in patients with recurrent glioblastoma

av Miller, Todd W., Traphagen, Nicole A., Li, Jing, Lewis, Lionel D., Lopes, Beatriz, Asthagiri, Ashok, Loomba, Johanna, De Jong, Jenny, Schiff, David, Patel, Sohil H., Purow, Benjamin W., Fadul, Camilo E.
I publikationen J Neurooncol (2019)

Endocytosis of very low-density lipoproteins: an unexpected mechanism for lipid acquisition by breast cancer cells

av Lupien, Leslie E., Bloch, Katarzyna, Dehairs, Jonas, Traphagen, Nicole A., Feng, William W., Davis, Wilson L., Dennis, Thea, Swinnen, Johannes V., Wells, Wendy A., Smits, Nicole C., Kuemmerle, Nancy B., Miller, Todd W., Kinlaw, William B.
I publikationen J Lipid Res (2020)

Therapeutically targeting tumor microenvironment–mediated drug resistance in estrogen receptor–positive breast cancer

av Shee, Kevin, Yang, Wei, Hinds, John W., Hampsch, Riley A., Varn, Frederick S., Traphagen, Nicole A., Patel, Kishan, Cheng, Chao, Jenkins, Nicole P., Kettenbach, Arminja N., Demidenko, Eugene, Owens, Philip, Faber, Anthony C., Golub, Todd R., Straussman, Ravid, Miller, Todd W.
I publikationen J Exp Med (2018)

A transcriptionally-definable subgroup of triple-negative breast and ovarian cancer samples shows sensitivity to HSP90 inhibition

av Shee, Kevin, Wells, Jason D., Ung, Matthew, Hampsch, Riley A., Traphagen, Nicole A., Yang, Wei, Liu, Stephanie, Zeldenrust, Megan A., Wang, Liewei, Kalari, Krishna R., Yu, Jia, Boughey, Judy C., Demidenko, Eugene, Kettenbach, Arminja N., Cheng, Chao, Goetz, Matthew P., Miller, Todd W.
I publikationen Clin Cancer Res (2019)

AMPK activation by metformin promotes survival of dormant ER+ breast cancer cells

av Hampsch, Riley A., Wells, Jason D., Traphagen, Nicole A., McCleery, Charlotte F., Fields, Jennifer L., Shee, Kevin, Dillon, Lloye M., Pooler, Darcy B., Lewis, Lionel D., Demidenko, Eugene, Huang, Yina H., Marotti, Jonathan D., Goen, Abigail E., Kinlaw, William B., Miller, Todd W.
I publikationen Clin Cancer Res (2020)