Endocytosis of very low-density lipoproteins: an unexpected mechanism for lipid acquisition by breast cancer cells

We previously described the expression of CD36 and LPL by breast cancer (BC) cells and tissues and the growth-promoting effect of VLDL observed only in the presence of LPL. We now report a model in which LPL is bound to a heparan sulfate proteoglycan motif on the BC cell surface and acts in concert...

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Publicat a:J Lipid Res
Autors principals: Lupien, Leslie E., Bloch, Katarzyna, Dehairs, Jonas, Traphagen, Nicole A., Feng, William W., Davis, Wilson L., Dennis, Thea, Swinnen, Johannes V., Wells, Wendy A., Smits, Nicole C., Kuemmerle, Nancy B., Miller, Todd W., Kinlaw, William B.
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Biochemistry and Molecular Biology 2020
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6997602/
https://ncbi.nlm.nih.gov/pubmed/31806729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.RA119000327
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