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Lipogenesis and lipolysis: the pathways exploited by the cancer cells to acquire fatty acids

One of the most important metabolic hallmarks of cancer cells is enhanced lipogenesis. Depending on the tumor type, tumor cells synthesize up to 95% of saturated and mono-unsaturated fatty acids (FA) de novo in spite of sufficient dietary lipid supply. This lipogenic conversion starts early when cel...

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Detalhes bibliográficos
Main Authors: Zaidi, Nousheen, Lupien, Leslie, Kuemmerle, Nancy B., Kinlaw, William B., Swinnen, Johannes V., Smans, Karine
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4002264/
https://ncbi.nlm.nih.gov/pubmed/24001676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.plipres.2013.08.005
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