Autophagy promotes escape from phosphatidylinositol 3-kinase inhibition in estrogen receptor–positive breast cancer

nork Yang, Wei, Hosford, Sarah R., Traphagen, Nicole A., Shee, Kevin, Demidenko, Eugene, Liu, Stephanie, Miller, Todd W.
Argitaratua izan da FASEB J (2018)

Estrogen receptor alpha drives mTORC1 inhibitor-induced feedback activation of PI3K/AKT in ER+ breast cancer

nork Yang, Wei, Schwartz, Gary N., Marotti, Jonathan D., Chen, Vivian, Traphagen, Nicole A., Gui, Jiang, Miller, Todd W.
Argitaratua izan da Oncotarget (2018)

High estrogen receptor alpha activation confers resistance to estrogen deprivation and is required for therapeutic response to estrogen in breast cancer

nork Traphagen, Nicole A., Hosford, Sarah R., Jiang, Amanda, Marotti, Jonathan D., Brauer, Brooke L., Demidenko, Eugene, Miller, Todd W.
Argitaratua izan da Oncogene (2021)

Estrogen therapy induces an unfolded protein response to drive cell death in ER+ breast cancer

nork Hosford, Sarah R., Shee, Kevin, Wells, Jason D., Traphagen, Nicole A., Fields, Jennifer L., Hampsch, Riley A., Kettenbach, Arminja N., Demidenko, Eugene, Miller, Todd W.
Argitaratua izan da Mol Oncol (2019)

Cytokine sensitivity screening highlights BMP4 pathway signaling as a therapeutic opportunity in ER(+) breast cancer

nork Shee, Kevin, Jiang, Amanda, Varn, Frederick S., Liu, Stephanie, Traphagen, Nicole A., Owens, Philip, Ma, Cynthia X., Hoog, Jeremy, Cheng, Chao, Golub, Todd R., Straussman, Ravid, Miller, Todd W.
Argitaratua izan da FASEB J (2019)

Exploiting mitochondrial and metabolic homeostasis as a vulnerability in NF1 deficient cells

nork Allaway, Robert J., Wood, Matthew D., Downey, Sondra L., Bouley, Stephanie J., Traphagen, Nicole A., Wells, Jason D., Batra, Jaya, Melancon, Sir Norman, Ringelberg, Carol, Seibel, William, Ratner, Nancy, Sanchez, Yolanda
Argitaratua izan da Oncotarget (2017)

Tumor pharmacokinetics and pharmacodynamics of the CDK4/6 inhibitor ribociclib in patients with recurrent glioblastoma

nork Miller, Todd W., Traphagen, Nicole A., Li, Jing, Lewis, Lionel D., Lopes, Beatriz, Asthagiri, Ashok, Loomba, Johanna, De Jong, Jenny, Schiff, David, Patel, Sohil H., Purow, Benjamin W., Fadul, Camilo E.
Argitaratua izan da J Neurooncol (2019)

Endocytosis of very low-density lipoproteins: an unexpected mechanism for lipid acquisition by breast cancer cells

nork Lupien, Leslie E., Bloch, Katarzyna, Dehairs, Jonas, Traphagen, Nicole A., Feng, William W., Davis, Wilson L., Dennis, Thea, Swinnen, Johannes V., Wells, Wendy A., Smits, Nicole C., Kuemmerle, Nancy B., Miller, Todd W., Kinlaw, William B.
Argitaratua izan da J Lipid Res (2020)

Therapeutically targeting tumor microenvironment–mediated drug resistance in estrogen receptor–positive breast cancer

nork Shee, Kevin, Yang, Wei, Hinds, John W., Hampsch, Riley A., Varn, Frederick S., Traphagen, Nicole A., Patel, Kishan, Cheng, Chao, Jenkins, Nicole P., Kettenbach, Arminja N., Demidenko, Eugene, Owens, Philip, Faber, Anthony C., Golub, Todd R., Straussman, Ravid, Miller, Todd W.
Argitaratua izan da J Exp Med (2018)

A transcriptionally-definable subgroup of triple-negative breast and ovarian cancer samples shows sensitivity to HSP90 inhibition

nork Shee, Kevin, Wells, Jason D., Ung, Matthew, Hampsch, Riley A., Traphagen, Nicole A., Yang, Wei, Liu, Stephanie, Zeldenrust, Megan A., Wang, Liewei, Kalari, Krishna R., Yu, Jia, Boughey, Judy C., Demidenko, Eugene, Kettenbach, Arminja N., Cheng, Chao, Goetz, Matthew P., Miller, Todd W.
Argitaratua izan da Clin Cancer Res (2019)

AMPK activation by metformin promotes survival of dormant ER+ breast cancer cells

nork Hampsch, Riley A., Wells, Jason D., Traphagen, Nicole A., McCleery, Charlotte F., Fields, Jennifer L., Shee, Kevin, Dillon, Lloye M., Pooler, Darcy B., Lewis, Lionel D., Demidenko, Eugene, Huang, Yina H., Marotti, Jonathan D., Goen, Abigail E., Kinlaw, William B., Miller, Todd W.
Argitaratua izan da Clin Cancer Res (2020)