Autophagy promotes escape from phosphatidylinositol 3-kinase inhibition in estrogen receptor–positive breast cancer

بواسطة Yang, Wei, Hosford, Sarah R., Traphagen, Nicole A., Shee, Kevin, Demidenko, Eugene, Liu, Stephanie, Miller, Todd W.
الحاوية / القاعدة FASEB J (2018)

Estrogen receptor alpha drives mTORC1 inhibitor-induced feedback activation of PI3K/AKT in ER+ breast cancer

بواسطة Yang, Wei, Schwartz, Gary N., Marotti, Jonathan D., Chen, Vivian, Traphagen, Nicole A., Gui, Jiang, Miller, Todd W.
الحاوية / القاعدة Oncotarget (2018)

High estrogen receptor alpha activation confers resistance to estrogen deprivation and is required for therapeutic response to estrogen in breast cancer

بواسطة Traphagen, Nicole A., Hosford, Sarah R., Jiang, Amanda, Marotti, Jonathan D., Brauer, Brooke L., Demidenko, Eugene, Miller, Todd W.
الحاوية / القاعدة Oncogene (2021)

Estrogen therapy induces an unfolded protein response to drive cell death in ER+ breast cancer

بواسطة Hosford, Sarah R., Shee, Kevin, Wells, Jason D., Traphagen, Nicole A., Fields, Jennifer L., Hampsch, Riley A., Kettenbach, Arminja N., Demidenko, Eugene, Miller, Todd W.
الحاوية / القاعدة Mol Oncol (2019)

Cytokine sensitivity screening highlights BMP4 pathway signaling as a therapeutic opportunity in ER(+) breast cancer

بواسطة Shee, Kevin, Jiang, Amanda, Varn, Frederick S., Liu, Stephanie, Traphagen, Nicole A., Owens, Philip, Ma, Cynthia X., Hoog, Jeremy, Cheng, Chao, Golub, Todd R., Straussman, Ravid, Miller, Todd W.
الحاوية / القاعدة FASEB J (2019)

Exploiting mitochondrial and metabolic homeostasis as a vulnerability in NF1 deficient cells

بواسطة Allaway, Robert J., Wood, Matthew D., Downey, Sondra L., Bouley, Stephanie J., Traphagen, Nicole A., Wells, Jason D., Batra, Jaya, Melancon, Sir Norman, Ringelberg, Carol, Seibel, William, Ratner, Nancy, Sanchez, Yolanda
الحاوية / القاعدة Oncotarget (2017)

Tumor pharmacokinetics and pharmacodynamics of the CDK4/6 inhibitor ribociclib in patients with recurrent glioblastoma

بواسطة Miller, Todd W., Traphagen, Nicole A., Li, Jing, Lewis, Lionel D., Lopes, Beatriz, Asthagiri, Ashok, Loomba, Johanna, De Jong, Jenny, Schiff, David, Patel, Sohil H., Purow, Benjamin W., Fadul, Camilo E.
الحاوية / القاعدة J Neurooncol (2019)

Endocytosis of very low-density lipoproteins: an unexpected mechanism for lipid acquisition by breast cancer cells

بواسطة Lupien, Leslie E., Bloch, Katarzyna, Dehairs, Jonas, Traphagen, Nicole A., Feng, William W., Davis, Wilson L., Dennis, Thea, Swinnen, Johannes V., Wells, Wendy A., Smits, Nicole C., Kuemmerle, Nancy B., Miller, Todd W., Kinlaw, William B.
الحاوية / القاعدة J Lipid Res (2020)

Therapeutically targeting tumor microenvironment–mediated drug resistance in estrogen receptor–positive breast cancer

بواسطة Shee, Kevin, Yang, Wei, Hinds, John W., Hampsch, Riley A., Varn, Frederick S., Traphagen, Nicole A., Patel, Kishan, Cheng, Chao, Jenkins, Nicole P., Kettenbach, Arminja N., Demidenko, Eugene, Owens, Philip, Faber, Anthony C., Golub, Todd R., Straussman, Ravid, Miller, Todd W.
الحاوية / القاعدة J Exp Med (2018)

A transcriptionally-definable subgroup of triple-negative breast and ovarian cancer samples shows sensitivity to HSP90 inhibition

بواسطة Shee, Kevin, Wells, Jason D., Ung, Matthew, Hampsch, Riley A., Traphagen, Nicole A., Yang, Wei, Liu, Stephanie, Zeldenrust, Megan A., Wang, Liewei, Kalari, Krishna R., Yu, Jia, Boughey, Judy C., Demidenko, Eugene, Kettenbach, Arminja N., Cheng, Chao, Goetz, Matthew P., Miller, Todd W.
الحاوية / القاعدة Clin Cancer Res (2019)

AMPK activation by metformin promotes survival of dormant ER+ breast cancer cells

بواسطة Hampsch, Riley A., Wells, Jason D., Traphagen, Nicole A., McCleery, Charlotte F., Fields, Jennifer L., Shee, Kevin, Dillon, Lloye M., Pooler, Darcy B., Lewis, Lionel D., Demidenko, Eugene, Huang, Yina H., Marotti, Jonathan D., Goen, Abigail E., Kinlaw, William B., Miller, Todd W.
الحاوية / القاعدة Clin Cancer Res (2020)