Hunting ALK to feed targeted cancer therapy

por Wellstein, Anton, Toretsky, Jeffrey A
Publicado no Nat Med (2011)

PTPL1: a large phosphatase with a split personality

por Abaan, Ogan D., Toretsky, Jeffrey A.
Publicado em 2008

Assemblages: Functional units formed by cellular phase separation

por Toretsky, Jeffrey A., Wright, Peter E.
Publicado em 2014

Oncogenic Partnerships: EWS-FLI1 Protein Interactions Initiate Key Pathways of Ewing’s Sarcoma

por Erkizan, Hayriye V., Uversky, Vladimir N., Toretsky, Jeffrey A.
Publicado em 2010

The Role of IGF-1R in Pediatric Malignancies

por Kim, Su Young, Toretsky, Jeffrey A., Scher, Daniel, Helman, Lee J.
Publicado em 2009

Valosin containing protein (VCP/p97) is a novel substrate for the protein tyrosine phosphatase PTPL1

por Abaan, Ogan D., Hendriks, Wiljan, Üren, Aykut, Toretsky, Jeffrey A., Erkizan, Hayriye V.
Publicado em 2012

Loss of SS18-SSX1 Inhibits Viability and Induces Apoptosis in Synovial Sarcoma

por Carmody Soni, Emily E., Schlottman, Silke, Erkizan, Hayriye V., Uren, Aykut, Toretsky, Jeffrey A.
Publicado em 2013

YK-4-279 Inhibits ERG and ETV1 Mediated Prostate Cancer Cell Invasion

por Rahim, Said, Beauchamp, Elspeth M., Kong, Yali, Brown, Milton L., Toretsky, Jeffrey A., Üren, Aykut
Publicado em 2011

Factor VII deficiency and developmental abnormalities in a patient with partial monosomy of 13q and trisomy of 16p: case report and review of the literature

por Brooks, Brian P, Meck, Jeanne M, Haddad, Bassem R, Bendavid, Claude, Blain, Delphine, Toretsky, Jeffrey A
Publicado em 2006

Wnt-3a and Dickkopf-1 Stimulate Neurite Outgrowth in Ewing Tumor Cells via a Frizzled3- and c-Jun N-Terminal Kinase-Dependent Mechanism

por Endo, Yoshimi, Beauchamp, Elspeth, Woods, David, Taylor, William G., Toretsky, Jeffrey A., Üren, Aykut, Rubin, Jeffrey S.
Publicado em 2008

Juvenile Xanthogranuloma in a Child with Previously Unsuspected Neurofibromatosis Type 1 and Juvenile Myelomonocytic Leukemia

por Raygada, Margarita, Arthur, Diane C., Wayne, Alan S., Rennert, Owen M., Toretsky, Jeffrey A., Stratakis, Constantine A.
Publicado em 2010

Design, Synthesis and Biological Evaluation of Ezrin Inhibitors Targeting Metastatic Osteosarcoma

por Paige, Mikell, Kosturko, George, Bulut, Gullay, Miessau, Matthew, Rahim, Said, Toretsky, Jeffrey A., Brown, Milton L., Üren, Aykut
Publicado no Bioorg Med Chem (2013)

Novel peptide binds EWS-FLI1 and reduces the oncogenic potential in Ewing tumors

por Erkizan, Hayriye V, Scher, Lauren J, Gamble, S Ellen, Barber-Rotenberg, Julie S, Sajwan, Kamal P, Üren, Aykut, Toretsky, Jeffrey A
Publicado em 2011

Acetylation Increases EWS-FLI1 DNA Binding and Transcriptional Activity

por Schlottmann, Silke, Erkizan, Hayriye V., Barber-Rotenberg, Julie S., Knights, Chad, Cheema, Amrita, Üren, Aykut, Avantaggiati, Maria L., Toretsky, Jeffrey A.
Publicado em 2012

Evaluation of Arsenic Trioxide by the Pediatric Preclinical Testing Program with a Focus on Ewing Sarcoma

por Smith, Malcolm A., Kang, Min H., Reynolds, C. Patrick, Kurmasheva, Raushan T., Alexander, Denise, Billups, Catherine A., Toretsky, Jeffrey A., Houghton, Peter J.
Publicado em 2012

Clofarabine induces ERK/MSK/CREB activation through inhibiting CD99 on Ewing sarcoma cells

por Sevim, Handan, Çelik, Haydar, Düşünceli, Levent, Ceyhan, Ceyda S., Molotkova, Anna, Nakazawa, Kay, Graham, Garrett T., Petro, Jeffrey R., Toretsky, Jeffrey A., Üren, Aykut
Publicado no PLoS One (2021)

Analysis of serum Insulin Growth Factor-1 concentrations in localized osteosarcoma: A Children’s Oncology Group Study

por Borinstein, Scott C., Barkauskas, Donald A., Bernstein, Mark, Goorin, Allen, Gorlick, Richard, Krailo, Mark, Schwartz, Cindy L., Wexler, Leonard H., Toretsky, Jeffrey A.
Publicado em 2013

High ALDH Activity Identifies Chemotherapy-Resistant Ewing's Sarcoma Stem Cells That Retain Sensitivity to EWS-FLI1 Inhibition

por Awad, Ola, Yustein, Jason T., Shah, Preeti, Gul, Naheed, Katuri, Varalakshmi, O'Neill, Alison, Kong, Yali, Brown, Milton L., Toretsky, Jeffrey A., Loeb, David M.
Publicado em 2010

Combining poly(ADP-ribose) polymerase 1 (PARP-1) inhibition and radiation in Ewing sarcoma results in lethal DNA damage

por Lee, Hae-June, Yoon, Changhwan, Schmidt, Benjamin, Park, Do Joong, Zhang, Alexia Y., Erkizan, Hayriye V., Toretsky, Jeffrey A., Kirsch, David G., Yoon, Sam S.
Publicado em 2013

Targeted Inhibition of Histone Deacetylase Leads to Suppression of Ewing Sarcoma Tumor Growth Through an Unappreciated EWS-FLI1/HDAC3/HSP90 Signaling Axis

por Ma, Yan, Baltezor, Michael, Rajewski, Lian, Crow, Jennifer, Samuel, Glenson, Staggs, Vincent S., Chastain, Katherine M., Toretsky, Jeffrey A., Weir, Scott J., Godwin, Andrew K.
Publicado no J Mol Med (Berl) (2019)