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Wnt-3a and Dickkopf-1 Stimulate Neurite Outgrowth in Ewing Tumor Cells via a Frizzled3- and c-Jun N-Terminal Kinase-Dependent Mechanism

Recombinant Wnt-3a stimulated the rapid formation of elongated processes in Ewing sarcoma family tumor (ESFT) cells that were identified as neurites. The processes stained positively for polymerized actin and microtubules as well as synapsin I and growth-associated protein 43. Inhibition of the Wnt...

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Detalhes bibliográficos
Main Authors: Endo, Yoshimi, Beauchamp, Elspeth, Woods, David, Taylor, William G., Toretsky, Jeffrey A., Üren, Aykut, Rubin, Jeffrey S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268413/
https://ncbi.nlm.nih.gov/pubmed/18212053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01780-07
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