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Casein kinase 1 delta functions at the centrosome to mediate Wnt-3a–dependent neurite outgrowth

Previously we determined that Dishevelled-2/3 (Dvl) mediate Wnt-3a–dependent neurite outgrowth in Ewing sarcoma family tumor cells. Here we report that neurite extension was associated with Dvl phosphorylation and that both were inhibited by the casein kinase 1 (CK1) δ/ε inhibitor IC261. Small inter...

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Detalhes bibliográficos
Main Authors: Greer, Yoshimi Endo, Rubin, Jeffrey S.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3063129/
https://ncbi.nlm.nih.gov/pubmed/21422228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201011111
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