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Wnt-3a and Dickkopf-1 Stimulate Neurite Outgrowth in Ewing Tumor Cells via a Frizzled3- and c-Jun N-Terminal Kinase-Dependent Mechanism

Recombinant Wnt-3a stimulated the rapid formation of elongated processes in Ewing sarcoma family tumor (ESFT) cells that were identified as neurites. The processes stained positively for polymerized actin and microtubules as well as synapsin I and growth-associated protein 43. Inhibition of the Wnt...

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Autori principali: Endo, Yoshimi, Beauchamp, Elspeth, Woods, David, Taylor, William G., Toretsky, Jeffrey A., Üren, Aykut, Rubin, Jeffrey S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268413/
https://ncbi.nlm.nih.gov/pubmed/18212053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01780-07
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