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Secreted Frizzled-related protein potentiation versus inhibition of Wnt3a/β-catenin signaling

Wnt signaling regulates a variety of cellular processes during embryonic development and in the adult. Many of these activities are mediated by the Frizzled family of seven-pass transmembrane receptors, which bind Wnts via a conserved cysteine-rich domain (CRD). Secreted Frizzled-related proteins (s...

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Bibliographische Detailangaben
Hauptverfasser: Xavier, Charles P., Melikova, Maria, Chuman, Yoshiro, Üren, Aykut, Baljinnyam, Bolormaa, Rubin, Jeffrey S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3953133/
https://ncbi.nlm.nih.gov/pubmed/24080158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2013.09.016
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