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Acetylation Increases EWS-FLI1 DNA Binding and Transcriptional Activity
Ewing Sarcoma (ES) is associated with a balanced chromosomal translocation that in most cases leads to the expression of the oncogenic fusion protein and transcription factor EWS-FLI1. EWS-FLI1 has been shown to be crucial for ES cell survival and tumor growth. However, its regulation is still enigm...
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Main Authors: | , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Frontiers Research Foundation
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3435532/ https://ncbi.nlm.nih.gov/pubmed/22973553 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2012.00107 |
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