Hunting ALK to feed targeted cancer therapy

by Wellstein, Anton, Toretsky, Jeffrey A
Published in Nat Med (2011)

PTPL1: a large phosphatase with a split personality

by Abaan, Ogan D., Toretsky, Jeffrey A.
Published 2008

Assemblages: Functional units formed by cellular phase separation

by Toretsky, Jeffrey A., Wright, Peter E.
Published 2014

Oncogenic Partnerships: EWS-FLI1 Protein Interactions Initiate Key Pathways of Ewing’s Sarcoma

by Erkizan, Hayriye V., Uversky, Vladimir N., Toretsky, Jeffrey A.
Published 2010

The Role of IGF-1R in Pediatric Malignancies

by Kim, Su Young, Toretsky, Jeffrey A., Scher, Daniel, Helman, Lee J.
Published 2009

Valosin containing protein (VCP/p97) is a novel substrate for the protein tyrosine phosphatase PTPL1

by Abaan, Ogan D., Hendriks, Wiljan, Üren, Aykut, Toretsky, Jeffrey A., Erkizan, Hayriye V.
Published 2012

Loss of SS18-SSX1 Inhibits Viability and Induces Apoptosis in Synovial Sarcoma

by Carmody Soni, Emily E., Schlottman, Silke, Erkizan, Hayriye V., Uren, Aykut, Toretsky, Jeffrey A.
Published 2013

YK-4-279 Inhibits ERG and ETV1 Mediated Prostate Cancer Cell Invasion

by Rahim, Said, Beauchamp, Elspeth M., Kong, Yali, Brown, Milton L., Toretsky, Jeffrey A., Üren, Aykut
Published 2011

Factor VII deficiency and developmental abnormalities in a patient with partial monosomy of 13q and trisomy of 16p: case report and review of the literature

by Brooks, Brian P, Meck, Jeanne M, Haddad, Bassem R, Bendavid, Claude, Blain, Delphine, Toretsky, Jeffrey A
Published 2006

Wnt-3a and Dickkopf-1 Stimulate Neurite Outgrowth in Ewing Tumor Cells via a Frizzled3- and c-Jun N-Terminal Kinase-Dependent Mechanism

by Endo, Yoshimi, Beauchamp, Elspeth, Woods, David, Taylor, William G., Toretsky, Jeffrey A., Üren, Aykut, Rubin, Jeffrey S.
Published 2008

Juvenile Xanthogranuloma in a Child with Previously Unsuspected Neurofibromatosis Type 1 and Juvenile Myelomonocytic Leukemia

by Raygada, Margarita, Arthur, Diane C., Wayne, Alan S., Rennert, Owen M., Toretsky, Jeffrey A., Stratakis, Constantine A.
Published 2010

Design, Synthesis and Biological Evaluation of Ezrin Inhibitors Targeting Metastatic Osteosarcoma

by Paige, Mikell, Kosturko, George, Bulut, Gullay, Miessau, Matthew, Rahim, Said, Toretsky, Jeffrey A., Brown, Milton L., Üren, Aykut
Published in Bioorg Med Chem (2013)

Novel peptide binds EWS-FLI1 and reduces the oncogenic potential in Ewing tumors

by Erkizan, Hayriye V, Scher, Lauren J, Gamble, S Ellen, Barber-Rotenberg, Julie S, Sajwan, Kamal P, Üren, Aykut, Toretsky, Jeffrey A
Published 2011

Acetylation Increases EWS-FLI1 DNA Binding and Transcriptional Activity

by Schlottmann, Silke, Erkizan, Hayriye V., Barber-Rotenberg, Julie S., Knights, Chad, Cheema, Amrita, Üren, Aykut, Avantaggiati, Maria L., Toretsky, Jeffrey A.
Published 2012

Evaluation of Arsenic Trioxide by the Pediatric Preclinical Testing Program with a Focus on Ewing Sarcoma

by Smith, Malcolm A., Kang, Min H., Reynolds, C. Patrick, Kurmasheva, Raushan T., Alexander, Denise, Billups, Catherine A., Toretsky, Jeffrey A., Houghton, Peter J.
Published 2012

Clofarabine induces ERK/MSK/CREB activation through inhibiting CD99 on Ewing sarcoma cells

by Sevim, Handan, Çelik, Haydar, Düşünceli, Levent, Ceyhan, Ceyda S., Molotkova, Anna, Nakazawa, Kay, Graham, Garrett T., Petro, Jeffrey R., Toretsky, Jeffrey A., Üren, Aykut
Published in PLoS One (2021)

Analysis of serum Insulin Growth Factor-1 concentrations in localized osteosarcoma: A Children’s Oncology Group Study

by Borinstein, Scott C., Barkauskas, Donald A., Bernstein, Mark, Goorin, Allen, Gorlick, Richard, Krailo, Mark, Schwartz, Cindy L., Wexler, Leonard H., Toretsky, Jeffrey A.
Published 2013

High ALDH Activity Identifies Chemotherapy-Resistant Ewing's Sarcoma Stem Cells That Retain Sensitivity to EWS-FLI1 Inhibition

by Awad, Ola, Yustein, Jason T., Shah, Preeti, Gul, Naheed, Katuri, Varalakshmi, O'Neill, Alison, Kong, Yali, Brown, Milton L., Toretsky, Jeffrey A., Loeb, David M.
Published 2010

Combining poly(ADP-ribose) polymerase 1 (PARP-1) inhibition and radiation in Ewing sarcoma results in lethal DNA damage

by Lee, Hae-June, Yoon, Changhwan, Schmidt, Benjamin, Park, Do Joong, Zhang, Alexia Y., Erkizan, Hayriye V., Toretsky, Jeffrey A., Kirsch, David G., Yoon, Sam S.
Published 2013

Targeted Inhibition of Histone Deacetylase Leads to Suppression of Ewing Sarcoma Tumor Growth Through an Unappreciated EWS-FLI1/HDAC3/HSP90 Signaling Axis

by Ma, Yan, Baltezor, Michael, Rajewski, Lian, Crow, Jennifer, Samuel, Glenson, Staggs, Vincent S., Chastain, Katherine M., Toretsky, Jeffrey A., Weir, Scott J., Godwin, Andrew K.
Published in J Mol Med (Berl) (2019)