p53 gain-of-function mutations promote metastasis via ENTPD5 upregulation and enhanced N-glycoprotein folding

Por Timofeev, Oleg, Stiewe, Thorsten
Publicado no Mol Cell Oncol (2017)

Rely on Each Other: DNA Binding Cooperativity Shapes p53 Functions in Tumor Suppression and Cancer Therapy

Por Timofeev, Oleg, Stiewe, Thorsten
Publicado no Cancers (Basel) (2021)

Inactivation of Mdm2 restores apoptosis proficiency of cooperativity mutant p53 in vivo

Por Klimovich, Boris, Stiewe, Thorsten, Timofeev, Oleg
Publicado no Cell Cycle (2019)

Cdc25 Phosphatases Are Required for Timely Assembly of CDK1-Cyclin B at the G(2)/M Transition

Por Timofeev, Oleg, Cizmecioglu, Onur, Settele, Florian, Kempf, Tore, Hoffmann, Ingrid
Publicado em 2010

Drying of Pigment-Cellulose Nanofibril Substrates

Por Timofeev, Oleg, Torvinen, Katariina, Sievänen, Jenni, Kaljunen, Timo, Kouko, Jarmo, Ketoja, Jukka A.
Publicado no Materials (Basel) (2014)

Loss of p53 function at late stages of tumorigenesis confers ARF-dependent vulnerability to p53 reactivation therapy

Por Klimovich, Boris, Mutlu, Samet, Schneikert, Jean, Elmshäuser, Sabrina, Klimovich, Maria, Nist, Andrea, Mernberger, Marco, Timofeev, Oleg, Stiewe, Thorsten
Publicado no Proc Natl Acad Sci U S A (2019)

Monitoring the dynamics of clonal tumour evolution in vivo using secreted luciferases

Por Charles, Joël P., Fuchs, Jeannette, Hefter, Mirjam, Vischedyk, Jonas B., Kleint, Maximilian, Vogiatzi, Fotini, Schäfer, Jonas A., Nist, Andrea, Timofeev, Oleg, Wanzel, Michael, Stiewe, Thorsten
Publicado em 2014

mTOR-mediated cancer drug resistance suppresses autophagy and generates a druggable metabolic vulnerability

Por Gremke, Niklas, Polo, Pierfrancesco, Dort, Aaron, Schneikert, Jean, Elmshäuser, Sabrina, Brehm, Corinna, Klingmüller, Ursula, Schmitt, Anna, Reinhardt, Hans Christian, Timofeev, Oleg, Wanzel, Michael, Stiewe, Thorsten
Publicado no Nat Commun (2020)

Residual apoptotic activity of a tumorigenic p53 mutant improves cancer therapy responses

Por Timofeev, Oleg, Klimovich, Boris, Schneikert, Jean, Wanzel, Michael, Pavlakis, Evangelos, Noll, Julia, Mutlu, Samet, Elmshäuser, Sabrina, Nist, Andrea, Mernberger, Marco, Lamp, Boris, Wenig, Ulrich, Brobeil, Alexander, Gattenlöhner, Stefan, Köhler, Kernt, Stiewe, Thorsten
Publicado no EMBO J (2019)

Mutant p53 promotes tumor progression and metastasis by the endoplasmic reticulum UDPase ENTPD5

Por Vogiatzi, Fotini, Brandt, Dominique T., Schneikert, Jean, Fuchs, Jeannette, Grikscheit, Katharina, Wanzel, Michael, Pavlakis, Evangelos, Charles, Joël P., Timofeev, Oleg, Nist, Andrea, Mernberger, Marco, Kantelhardt, Eva J., Siebolts, Udo, Bartel, Frank, Jacob, Ralf, Rath, Ariane, Moll, Roland, Grosse, Robert, Stiewe, Thorsten
Publicado no Proc Natl Acad Sci U S A (2016)