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p53 gain-of-function mutations promote metastasis via ENTPD5 upregulation and enhanced N-glycoprotein folding

Mutations in cancer abolish normal tumor suppressive functions of tumor protein p53 (TP53, best known as p53) and convert it into an oncogene. We recently reported the identification of ectonucleoside triphosphate diphosphohydrolase 5 (ENTPD5) as a transcriptional target of mutant p53 that enhances...

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Detalhes bibliográficos
Publicado no:Mol Cell Oncol
Main Authors: Timofeev, Oleg, Stiewe, Thorsten
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5383355/
https://ncbi.nlm.nih.gov/pubmed/28401189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2017.1288678
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