p53 gain-of-function mutations promote metastasis via ENTPD5 upregulation and enhanced N-glycoprotein folding

Mutations in cancer abolish normal tumor suppressive functions of tumor protein p53 (TP53, best known as p53) and convert it into an oncogene. We recently reported the identification of ectonucleoside triphosphate diphosphohydrolase 5 (ENTPD5) as a transcriptional target of mutant p53 that enhances...

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Bibliographic Details
Published in:Mol Cell Oncol
Main Authors: Timofeev, Oleg, Stiewe, Thorsten
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5383355/
https://ncbi.nlm.nih.gov/pubmed/28401189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2017.1288678
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