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p53 gain-of-function mutations promote metastasis via ENTPD5 upregulation and enhanced N-glycoprotein folding

Mutations in cancer abolish normal tumor suppressive functions of tumor protein p53 (TP53, best known as p53) and convert it into an oncogene. We recently reported the identification of ectonucleoside triphosphate diphosphohydrolase 5 (ENTPD5) as a transcriptional target of mutant p53 that enhances...

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Bibliografische gegevens
Gepubliceerd in:Mol Cell Oncol
Hoofdauteurs: Timofeev, Oleg, Stiewe, Thorsten
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Taylor & Francis 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5383355/
https://ncbi.nlm.nih.gov/pubmed/28401189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2017.1288678
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