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Cdc25 Phosphatases Are Required for Timely Assembly of CDK1-Cyclin B at the G(2)/M Transition
Progression through mitosis requires the coordinated regulation of Cdk1 kinase activity. Activation of Cdk1 is a multistep process comprising binding of Cdk1 to cyclin B, relocation of cyclin-kinase complexes to the nucleus, activating phosphorylation of Cdk1 on Thr(161) by the Cdk-activating kinase...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2010
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2878026/ https://ncbi.nlm.nih.gov/pubmed/20360007 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.096552 |
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