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Cdc25 Phosphatases Are Required for Timely Assembly of CDK1-Cyclin B at the G(2)/M Transition

Progression through mitosis requires the coordinated regulation of Cdk1 kinase activity. Activation of Cdk1 is a multistep process comprising binding of Cdk1 to cyclin B, relocation of cyclin-kinase complexes to the nucleus, activating phosphorylation of Cdk1 on Thr(161) by the Cdk-activating kinase...

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Hlavní autoři: Timofeev, Oleg, Cizmecioglu, Onur, Settele, Florian, Kempf, Tore, Hoffmann, Ingrid
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2878026/
https://ncbi.nlm.nih.gov/pubmed/20360007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.096552
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