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Phosphorylation and activation of the Xenopus Cdc25 phosphatase in the absence of Cdc2 and Cdk2 kinase activity.

The M-phase inducer, Cdc25C, is a dual-specificity phosphatase that directly phosphorylates and activates the cyclin B/Cdc2 kinase complex, leading to initiation of mitosis. Cdc25 itself is activated at the G2/M transition by phosphorylation on serine and threonine residues. Previously, it was demon...

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Библиографические подробности
Опубликовано в: :Mol Biol Cell
Главные авторы: Izumi, T, Maller, J L
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Cell Biology 1995
Предметы:
Online-ссылка:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC275830/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7787247/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.6.2.215
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