Phosphorylation and activation of the Xenopus Cdc25 phosphatase in the absence of Cdc2 and Cdk2 kinase activity.

The M-phase inducer, Cdc25C, is a dual-specificity phosphatase that directly phosphorylates and activates the cyclin B/Cdc2 kinase complex, leading to initiation of mitosis. Cdc25 itself is activated at the G2/M transition by phosphorylation on serine and threonine residues. Previously, it was demon...

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Vydáno v:	Mol Biol Cell
Hlavní autoři:	Izumi, T, Maller, J L
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Cell Biology 1995
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC275830/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7787247/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.6.2.215
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