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Ectopic Expression of Cdc25A Accelerates the G(1)/S Transition and Leads to Premature Activation of Cyclin E- and Cyclin A-Dependent Kinases

Human Cdc25 phosphatases play important roles in cell cycle regulation by removing inhibitory phosphates from tyrosine and threonine residues of cyclin-dependent kinases. Three human Cdc25 isoforms, A, B, and C, have been discovered. Cdc25B and Cdc25C play crucial roles at the G(2)/M transition. In...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Blomberg, Ida, Hoffmann, Ingrid
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 1999
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC84557/
https://ncbi.nlm.nih.gov/pubmed/10454565
Etiketak: Etiketa erantsi
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