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Ectopic Expression of Cdc25A Accelerates the G(1)/S Transition and Leads to Premature Activation of Cyclin E- and Cyclin A-Dependent Kinases
Human Cdc25 phosphatases play important roles in cell cycle regulation by removing inhibitory phosphates from tyrosine and threonine residues of cyclin-dependent kinases. Three human Cdc25 isoforms, A, B, and C, have been discovered. Cdc25B and Cdc25C play crucial roles at the G(2)/M transition. In...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
1999
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC84557/ https://ncbi.nlm.nih.gov/pubmed/10454565 |
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