Affimer proteins for F-actin: novel affinity reagents that label F-actin in live and fixed cells

por Lopata, Anna, Hughes, Ruth, Tiede, Christian, Heissler, Sarah M., Sellers, James R., Knight, Peter J., Tomlinson, Darren, Peckham, Michelle
Publicado no Sci Rep (2018)

Development of an Affimer-antibody combined immunological diagnosis kit for glypican-3

por Xie, Chunmei, Tiede, Christian, Zhang, Xuanyi, Wang, Congrong, Li, Zhixiong, Xu, Xiao, McPherson, Michael J., Tomlinson, Darren C., Xu, Weiwen
Publicado no Sci Rep (2017)

Ultraefficient Cap-Exchange Protocol To Compact Biofunctional Quantum Dots for Sensitive Ratiometric Biosensing and Cell Imaging

por Wang, Weili, Guo, Yuan, Tiede, Christian, Chen, Siyuan, Kopytynski, Michal, Kong, Yifei, Kulak, Alexander, Tomlinson, Darren, Chen, Rongjun, McPherson, Michael, Zhou, Dejian
Publicado no ACS Appl Mater Interfaces (2017)

Affimer reagents as tools in diagnosing plant virus diseases

por Hesketh, Emma L., Tiede, Christian, Adamson, Hope, Adams, Thomas L., Byrne, Matthew J., Meshcheriakova, Yulia, Kruse, Inga, McPherson, Michael J., Lomonossoff, George P., Tomlinson, Darren C., Ranson, Neil A.
Publicado no Sci Rep (2019)

Adhiron: a stable and versatile peptide display scaffold for molecular recognition applications

por Tiede, Christian, Tang, Anna A. S., Deacon, Sarah E., Mandal, Upasana, Nettleship, Joanne E., Owen, Robin L., George, Suja E., Harrison, David J., Owens, Raymond J., Tomlinson, Darren C., McPherson, Michael J.
Publicado em 2014

Fibrinogen interaction with complement C3: a potential therapeutic target to reduce thrombosis risk

por King, Rhodri J., Schuett, Katharina, Tiede, Christian, Jankowski, Vera, John, Vicky, Trehan, Abhi, Simmons, Katie, Ponnambalam, Sreenivasan, Storey, Robert F., Fishwick, Colin W.G., McPherson, Michael J., Tomlinson, Darren C., Ajjan, Ramzi A.
Publicado no Haematologica (2020)

Trivalent Gd-DOTA reagents for modification of proteins

por Fisher, Martin J., Williamson, Daniel J., Burslem, George M., Plante, Jeffrey P., Manfield, Iain W., Tiede, Christian, Ault, James R., Stockley, Peter G., Plein, Sven, Maqbool, Azhar, Tomlinson, Darren C., Foster, Richard, Warriner, Stuart L., Bon, Robin S.
Publicado no RSC Adv (2015)

Characterization and applications of a Crimean-Congo hemorrhagic fever virus nucleoprotein-specific Affimer: Inhibitory effects in viral replication and development of colorimetric...

por Álvarez-Rodríguez, Beatriz, Tiede, Christian, Hoste, Alexis C. R., Surtees, Rebecca A., Trinh, Chi H., Slack, Gillian S., Chamberlain, John, Hewson, Roger, Fresco, Alba, Sastre, Patricia, Tomlinson, Darren C., Millner, Paul A., Edwards, Thomas A., Barr, John N.
Publicado no PLoS Negl Trop Dis (2020)

Nanoscale Pattern Extraction from Relative Positions of Sparse 3D Localizations

por Curd, Alistair P., Leng, Joanna, Hughes, Ruth E., Cleasby, Alexa J., Rogers, Brendan, Trinh, Chi H., Baird, Michelle A., Takagi, Yasuharu, Tiede, Christian, Sieben, Christian, Manley, Suliana, Schlichthaerle, Thomas, Jungmann, Ralf, Ries, Jonas, Shroff, Hari, Peckham, Michelle
Publicado no Nano Lett (2020)

Generation of specific inhibitors of SUMO1- and SUMO2/3-mediated protein-protein interactions using Affimer (Adhiron) technology

por Hughes, David J., Tiede, Christian, Penswick, Natalie, Tang, Anna A. S., Trinh, Chi H., Mandal, Upasana, Zajac, Katarzyna Z., Gaule, Thembaninskosi, Howell, Gareth, Edwards, Thomas A., Duan, Jianxin, Feyfant, Eric, McPherson, Michael J., Tomlinson, Darren C., Whitehouse, Adrian
Publicado no Sci Signal (2017)

Selective Affimers Recognise the BCL‐2 Family Proteins BCL‐x(L) and MCL‐1 through Noncanonical Structural Motifs

por Miles, Jennifer A., Hobor, Fruzsina, Trinh, Chi H., Taylor, James, Tiede, Christian, Rowell, Philip R., Jackson, Brian R., Nadat, Fatima A., Ramsahye, Pallavi, Kyle, Hannah F., Wicky, Basile I. M., Clarke, Jane, Tomlinson, Darren C., Wilson, Andrew J., Edwards, Thomas A.
Publicado no Chembiochem (2020)

Affimer proteins as a tool to modulate fibrinolysis, stabilize the blood clot, and reduce bleeding complications

por Kearney, Katherine J., Pechlivani, Nikoletta, King, Rhodri, Tiede, Christian, Phoenix, Fladia, Cheah, Ramsah, Macrae, Fraser L., Simmons, Katie J., Manfield, Iain W., Smith, Kerrie A., Spurgeon, Benjamin E. J., Naseem, Khalid M., Ariens, Robert A. S., McPherson, Michael J., Tomlinson, Darren C., Ajjan, Ramzi A.
Publicado no Blood (2019)

Affimer proteins inhibit immune complex binding to FcγRIIIa with high specificity through competitive and allosteric modes of action

por Robinson, James I., Baxter, Euan W., Owen, Robin L., Thomsen, Maren, Tomlinson, Darren C., Waterhouse, Mark P., Win, Stephanie J., Nettleship, Joanne E., Tiede, Christian, Foster, Richard J., Owens, Raymond J., Fishwick, Colin W. G., Harris, Sarah A., Goldman, Adrian, McPherson, Michael J., Morgan, Ann W.
Publicado no Proc Natl Acad Sci U S A (2018)

RAS-inhibiting biologics identify and probe druggable pockets including an SII-α3 allosteric site

por Haza, Katarzyna Z., Martin, Heather L., Rao, Ajinkya, Turner, Amy L., Saunders, Sophie E., Petersen, Britta, Tiede, Christian, Tipping, Kevin, Tang, Anna A., Ajayi, Modupe, Taylor, Thomas, Harvey, Maia, Fishwick, Keri M., Adams, Thomas L., Gaule, Thembaninkosi G., Trinh, Chi H., Johnson, Matthew, Breeze, Alexander L., Edwards, Thomas A., McPherson, Michael J., Tomlinson, Darren C.
Publicado no Nat Commun (2021)

Affimer proteins are versatile and renewable affinity reagents

por Tiede, Christian, Bedford, Robert, Heseltine, Sophie J, Smith, Gina, Wijetunga, Imeshi, Ross, Rebecca, AlQallaf, Danah, Roberts, Ashley PE, Balls, Alexander, Curd, Alistair, Hughes, Ruth E, Martin, Heather, Needham, Sarah R, Zanetti-Domingues, Laura C, Sadigh, Yashar, Peacock, Thomas P, Tang, Anna A, Gibson, Naomi, Kyle, Hannah, Platt, Geoffrey W, Ingram, Nicola, Taylor, Thomas, Coletta, Louise P, Manfield, Iain, Knowles, Margaret, Bell, Sandra, Esteves, Filomena, Maqbool, Azhar, Prasad, Raj K, Drinkhill, Mark, Bon, Robin S, Patel, Vikesh, Goodchild, Sarah A, Martin-Fernandez, Marisa, Owens, Ray J, Nettleship, Joanne E, Webb, Michael E, Harrison, Michael, Lippiat, Jonathan D, Ponnambalam, Sreenivasan, Peckham, Michelle, Smith, Alastair, Ferrigno, Paul Ko, Johnson, Matt, McPherson, Michael J, Tomlinson, Darren Charles
Publicado no eLife (2017)