Are cells from a snowman realistic? Cryopreserved tissues as a source for single-cell RNA-sequencing experiments

Por Vieira Braga, Felipe A., Teichmann, Sarah A., Stubbington, Michael J. T.
Publicado no Genome Biol (2017)

Single cell transcriptomics to explore the immune system in health and disease†

Por Stubbington, Michael J.T., Rozenblatt-Rosen, Orit, Regev, Aviv, Teichmann, Sarah A.
Publicado no Science (2017)

Intrinsic transcriptional heterogeneity in B cells controls early class switching to IgE

Por Wu, Yee Ling, Stubbington, Michael J.T., Daly, Maria, Teichmann, Sarah A., Rada, Cristina
Publicado no J Exp Med (2017)

T cell fate and clonality inference from single cell transcriptomes

Por Stubbington, Michael J.T., Lönnberg, Tapio, Proserpio, Valentina, Clare, Simon, Speak, Anneliese O., Dougan, Gordon, Teichmann, Sarah A.
Publicado no Nat Methods (2016)

Single-cell transcriptome analysis of fish immune cells provides insight into the evolution of vertebrate immune cell types

Por Carmona, Santiago J., Teichmann, Sarah A., Ferreira, Lauren, Macaulay, Iain C., Stubbington, Michael J.T., Cvejic, Ana, Gfeller, David
Publicado no Genome Res (2017)

The Regulatory T Cell Lineage Factor Foxp3 Regulates Gene Expression through Several Distinct Mechanisms Mostly Independent of Direct DNA Binding

Por Xie, Xin, Stubbington, Michael J. T., Nissen, Jesper K., Andersen, Kristian G., Hebenstreit, Daniel, Teichmann, Sarah A., Betz, Alexander G.
Publicado no PLoS Genet (2015)

Two Mutually Exclusive Local Chromatin States Drive Efficient V(D)J Recombination

Por Bolland, Daniel J., Koohy, Hashem, Wood, Andrew L., Matheson, Louise S., Krueger, Felix, Stubbington, Michael J.T., Baizan-Edge, Amanda, Chovanec, Peter, Stubbs, Bryony A., Tabbada, Kristina, Andrews, Simon R., Spivakov, Mikhail, Corcoran, Anne E.
Publicado no Cell Rep (2016)

Aging increases cell-to-cell transcriptional variability upon immune stimulation

Por Martinez-Jimenez, Celia Pilar, Eling, Nils, Chen, Hung-Chang, Vallejos, Catalina A., Kolodziejczyk, Aleksandra A., Connor, Frances, Stojic, Lovorka, Rayner, Timothy F., Stubbington, Michael J.T., Teichmann, Sarah A., de la Roche, Maike, Marioni, John C., Odom, Duncan T.
Publicado no Science (2017)

Circulating and Tissue-Resident CD4(+) T Cells With Reactivity to Intestinal Microbiota Are Abundant in Healthy Individuals and Function Is Altered During Inflammation

Por Hegazy, Ahmed N., West, Nathaniel R., Stubbington, Michael J.T., Wendt, Emily, Suijker, Kim I.M., Datsi, Angeliki, This, Sebastien, Danne, Camille, Campion, Suzanne, Duncan, Sylvia H., Owens, Benjamin M.J., Uhlig, Holm H., McMichael, Andrew, Bergthaler, Andreas, Teichmann, Sarah A., Keshav, Satish, Powrie, Fiona
Publicado no Gastroenterology (2017)

Single-cell RNA-seq and computational analysis using temporal mixture modelling resolves Th1/Tfh fate bifurcation in malaria

Por Lönnberg, Tapio, Svensson, Valentine, James, Kylie R., Fernandez-Ruiz, Daniel, Sebina, Ismail, Montandon, Ruddy, Soon, Megan S. F., Fogg, Lily G., Nair, Arya Sheela, Liligeto, Urijah, Stubbington, Michael J. T., Ly, Lam-Ha, Bagger, Frederik Otzen, Zwiessele, Max, Lawrence, Neil D., Souza-Fonseca-Guimaraes, Fernando, Bunn, Patrick T., Engwerda, Christian R., Heath, William R., Billker, Oliver, Stegle, Oliver, Haque, Ashraful, Teichmann, Sarah A.
Publicado no Sci Immunol (2017)