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Single-cell transcriptome analysis of fish immune cells provides insight into the evolution of vertebrate immune cell types

The immune system of vertebrate species consists of many different cell types that have distinct functional roles and are subject to different evolutionary pressures. Here, we first analyzed conservation of genes specific for all major immune cell types in human and mouse. Our results revealed highe...

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Publicat a:Genome Res
Autors principals: Carmona, Santiago J., Teichmann, Sarah A., Ferreira, Lauren, Macaulay, Iain C., Stubbington, Michael J.T., Cvejic, Ana, Gfeller, David
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5340972/
https://ncbi.nlm.nih.gov/pubmed/28087841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.207704.116
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