2-Hydroxyglutarate is not a metabolite; d-2-hydroxyglutarate and l-2-hydroxyglutarate are!

di Struys, Eduard A.
Pubblicazione 2013

Progress in understanding 2-hydroxyglutaric acidurias

di Kranendijk, Martijn, Struys, Eduard A., Salomons, Gajja S., Van der Knaap, Marjo S., Jakobs, Cornelis
Pubblicazione 2012

The measurement of urinary Δ(1)-piperideine-6-carboxylate, the alter ego of α-aminoadipic semialdehyde, in Antiquitin deficiency

di Struys, Eduard A., Bok, Levinus A., Emal, Dina, Houterman, Saskia, Willemsen, Michel A., Jakobs, Cornelis
Pubblicazione 2012

A catabolic block does not sufficiently explain how 2-deoxy-d-glucose inhibits cell growth

di Ralser, Markus, Wamelink, Mirjam M., Struys, Eduard A., Joppich, Christian, Krobitsch, Sylvia, Jakobs, Cornelis, Lehrach, Hans
Pubblicazione 2008

Ribose-5-Phosphate Isomerase Deficiency: New Inborn Error in the Pentose Phosphate Pathway Associated with a Slowly Progressive Leukoencephalopathy

di Huck, Jojanneke H. J., Verhoeven, Nanda M., Struys, Eduard A., Salomons, Gajja S., Jakobs, Cornelis, van der Knaap, Marjo S.
Pubblicazione 2004

Human iPSCs harbor homoplasmic and heteroplasmic mitochondrial DNA mutations while maintaining hESC-like metabolic reprogramming

di Prigione, Alessandro, Lichtner, Björn, Kuhl, Heiner, Struys, Eduard A., Wamelink, Mirjam, Lehrach, Hans, Ralser, Markus, Timmermann, Bernd, Adjaye, James
Pubblicato in Stem Cells (2014)

Mutations in the d-2-Hydroxyglutarate Dehydrogenase Gene Cause d-2-Hydroxyglutaric Aciduria

di Struys, Eduard A., Salomons, Gajja S., Achouri, Younes, Van Schaftingen, Emile, Grosso, Salvatore, Craigen, William J., Verhoeven, Nanda M., Jakobs, Cornelis
Pubblicazione 2005

Guanidinoacetate Methyltransferase Activity in Lymphocytes, for a Fast Diagnosis

di Berends, Lisette M., Struys, Eduard A., Roos, Birthe, Holwerda, Ulbe, Jansen, Erwin E. W., Salomons, Gajja S., Wamelink, Mirjam M. C.
Pubblicato in JIMD Rep (2017)

Evidence for Altered Glutamine Metabolism in Human Immunodeficiency Virus Type 1 Infected Primary Human CD4(+) T Cells

di Hegedus, Andrea, Kavanagh Williamson, Maia, Khan, Mariam B., Dias Zeidler, Julianna, Da Poian, Andrea T., El-Bacha, Tatiana, Struys, Eduard A., Huthoff, Hendrik
Pubblicato in AIDS Res Hum Retroviruses (2017)

No evidence for cell‐to‐cell transmission of the unfolded protein response in cell culture

di van Ziel, Anna M., Wolzak, Kimberly, Nölle, Anna, Hoetjes, Petrus J., Berenjeno‐Correa, Ernesto, van Anken, Eelco, Struys, Eduard A., Scheper, Wiep
Pubblicato in J Neurochem (2019)

Transaldolase Deficiency: Liver Cirrhosis Associated with a New Inborn Error in the Pentose Phosphate Pathway

di Verhoeven, Nanda M., Huck, Jojanneke H. J., Roos, Birthe, Struys, Eduard A., Salomons, Gajja S., Douwes, Adriaan C., van der Knaap, Marjo S., Jakobs, Cornelis
Pubblicazione 2001

Dynamic rerouting of the carbohydrate flux is key to counteracting oxidative stress

di Ralser, Markus, Wamelink, Mirjam M, Kowald, Axel, Gerisch, Birgit, Heeren, Gino, Struys, Eduard A, Klipp, Edda, Jakobs, Cornelis, Breitenbach, Michael, Lehrach, Hans, Krobitsch, Sylvia
Pubblicazione 2007

Frequent reconstitution of IDH2(R140Q) mutant clonal multilineage hematopoiesis following chemotherapy for acute myeloid leukemia

di Wiseman, Daniel H., Williams, Emma L., Wilks, Deepti P., Sun Leong, Hui, Somerville, Tim D. D., Dennis, Michael W., Struys, Eduard A., Bakkali, Abdellatif, Salomons, Gajja S., Somervaille, Tim C. P.
Pubblicato in Leukemia (2016)

IDH1-mutated transgenic zebrafish lines: An in-vivo model for drug screening and functional analysis

di Gao, Ya, de Wit, Maurice, Struys, Eduard A., van der Linde, Herma C. Z., Salomons, Gajja S., Lamfers, Martine L. M., Willemsen, Rob, Sillevis Smitt, Peter A. E., French, Pim J.
Pubblicato in PLoS One (2018)

A Phase Ib Clinical Trial of Metformin and Chloroquine in Patients with IDH1-Mutated Solid Tumors

di Khurshed, Mohammed, Molenaar, Remco J., van Linde, Myra E., Mathôt, Ron A., Struys, Eduard A., van Wezel, Tom, van Noorden, Cornelis J. F., Klümpen, Heinz-Josef, Bovée, Judith V. M. G., Wilmink, Johanna W.
Pubblicato in Cancers (Basel) (2021)

In vivo efficacy of mutant IDH1 inhibitor HMS-101 and structural resolution of distinct binding site

di Chaturvedi, Anuhar, Goparaju, Ramya, Gupta, Charu, Weder, Julia, Klünemann, Thomas, Araujo Cruz, Michelle Maria, Kloos, Arnold, Goerlich, Kerstin, Schottmann, Renate, Othman, Basem, Struys, Eduard A., Bähre, Heike, Grote-Koska, Denis, Brand, Korbinian, Ganser, Arnold, Preller, Matthias, Heuser, Michael
Pubblicato in Leukemia (2019)

Enantiomer-specific and paracrine leukemogenicity of mutant IDH metabolite 2-hydroxyglutarate

di Chaturvedi, Anuhar, Araujo Cruz, Michelle Maria, Jyotsana, Nidhi, Sharma, Amit, Goparaju, Ramya, Schwarzer, Adrian, Görlich, Kerstin, Schottmann, Renate, Struys, Eduard A., Jansen, Erwin E., Rohde, Christian, Müller-Tidow, Carsten, Geffers, Robert, Göhring, Gudrun, Ganser, Arnold, Thol, Felicitas, Heuser, Michael
Pubblicato in Leukemia (2016)

TM-04 A TRANSGENIC ZEBRAFISH MODEL FOR GLIOMAS WITH MUTATIONS IN ISOCITRATE DEHYDROGENASE 1

di Gao, Ya D., van der Linde, Herma C. Z., Struys, Eduard A., van Breugel, Valeska, de Wit, Maurice, Erdem, Lale, Bovée, Judith V.M.G., Lamfers, Martine L. M., Silleviss Smitt, Peter A.E., Salomons, Gajja S., Willemsen, Rob, French, Pim J.
Pubblicato in Neuro Oncol (2014)

D‐2‐hydroxyglutaric aciduria Type I: Functional analysis of D2HGDH missense variants

di Pop, Ana, Struys, Eduard A., Jansen, Erwin E. W., Fernandez, Matilde R., Kanhai, Warsha A., van Dooren, Silvy J. M., Ozturk, Senay, van Oostendorp, Justin, Lennertz, Pascal, Kranendijk, Martijn, van der Knaap, Marjo S., Gibson, K. Michael, van Schaftingen, Emile, Salomons, Gajja S.
Pubblicato in Hum Mutat (2019)

Inhibition of mutant IDH1 decreases D-2-HG levels without affecting tumorigenic properties of chondrosarcoma cell lines

di Suijker, Johnny, Oosting, Jan, Koornneef, Annemarie, Struys, Eduard A., Salomons, Gajja S., Schaap, Frank G., Waaijer, Cathelijn J.F., Wijers-Koster, Pauline M., Briaire-de Bruijn, Inge H., Haazen, Lizette, Riester, Scott M., Dudakovic, Amel, Danen, Erik, Cleton-Jansen, Anne-Marie, van Wijnen, Andre J., Bovée, Judith V.M.G.
Pubblicato in Oncotarget (2015)