2-Hydroxyglutarate is not a metabolite; d-2-hydroxyglutarate and l-2-hydroxyglutarate are!

Autor Struys, Eduard A.
Vydáno 2013

Progress in understanding 2-hydroxyglutaric acidurias

Autor Kranendijk, Martijn, Struys, Eduard A., Salomons, Gajja S., Van der Knaap, Marjo S., Jakobs, Cornelis
Vydáno 2012

The measurement of urinary Δ(1)-piperideine-6-carboxylate, the alter ego of α-aminoadipic semialdehyde, in Antiquitin deficiency

Autor Struys, Eduard A., Bok, Levinus A., Emal, Dina, Houterman, Saskia, Willemsen, Michel A., Jakobs, Cornelis
Vydáno 2012

A catabolic block does not sufficiently explain how 2-deoxy-d-glucose inhibits cell growth

Autor Ralser, Markus, Wamelink, Mirjam M., Struys, Eduard A., Joppich, Christian, Krobitsch, Sylvia, Jakobs, Cornelis, Lehrach, Hans
Vydáno 2008

Ribose-5-Phosphate Isomerase Deficiency: New Inborn Error in the Pentose Phosphate Pathway Associated with a Slowly Progressive Leukoencephalopathy

Autor Huck, Jojanneke H. J., Verhoeven, Nanda M., Struys, Eduard A., Salomons, Gajja S., Jakobs, Cornelis, van der Knaap, Marjo S.
Vydáno 2004

Human iPSCs harbor homoplasmic and heteroplasmic mitochondrial DNA mutations while maintaining hESC-like metabolic reprogramming

Autor Prigione, Alessandro, Lichtner, Björn, Kuhl, Heiner, Struys, Eduard A., Wamelink, Mirjam, Lehrach, Hans, Ralser, Markus, Timmermann, Bernd, Adjaye, James
Vydáno v Stem Cells (2014)

Mutations in the d-2-Hydroxyglutarate Dehydrogenase Gene Cause d-2-Hydroxyglutaric Aciduria

Autor Struys, Eduard A., Salomons, Gajja S., Achouri, Younes, Van Schaftingen, Emile, Grosso, Salvatore, Craigen, William J., Verhoeven, Nanda M., Jakobs, Cornelis
Vydáno 2005

Guanidinoacetate Methyltransferase Activity in Lymphocytes, for a Fast Diagnosis

Autor Berends, Lisette M., Struys, Eduard A., Roos, Birthe, Holwerda, Ulbe, Jansen, Erwin E. W., Salomons, Gajja S., Wamelink, Mirjam M. C.
Vydáno v JIMD Rep (2017)

Evidence for Altered Glutamine Metabolism in Human Immunodeficiency Virus Type 1 Infected Primary Human CD4(+) T Cells

Autor Hegedus, Andrea, Kavanagh Williamson, Maia, Khan, Mariam B., Dias Zeidler, Julianna, Da Poian, Andrea T., El-Bacha, Tatiana, Struys, Eduard A., Huthoff, Hendrik
Vydáno v AIDS Res Hum Retroviruses (2017)

No evidence for cell‐to‐cell transmission of the unfolded protein response in cell culture

Autor van Ziel, Anna M., Wolzak, Kimberly, Nölle, Anna, Hoetjes, Petrus J., Berenjeno‐Correa, Ernesto, van Anken, Eelco, Struys, Eduard A., Scheper, Wiep
Vydáno v J Neurochem (2019)

Transaldolase Deficiency: Liver Cirrhosis Associated with a New Inborn Error in the Pentose Phosphate Pathway

Autor Verhoeven, Nanda M., Huck, Jojanneke H. J., Roos, Birthe, Struys, Eduard A., Salomons, Gajja S., Douwes, Adriaan C., van der Knaap, Marjo S., Jakobs, Cornelis
Vydáno 2001

Dynamic rerouting of the carbohydrate flux is key to counteracting oxidative stress

Autor Ralser, Markus, Wamelink, Mirjam M, Kowald, Axel, Gerisch, Birgit, Heeren, Gino, Struys, Eduard A, Klipp, Edda, Jakobs, Cornelis, Breitenbach, Michael, Lehrach, Hans, Krobitsch, Sylvia
Vydáno 2007

Frequent reconstitution of IDH2(R140Q) mutant clonal multilineage hematopoiesis following chemotherapy for acute myeloid leukemia

Autor Wiseman, Daniel H., Williams, Emma L., Wilks, Deepti P., Sun Leong, Hui, Somerville, Tim D. D., Dennis, Michael W., Struys, Eduard A., Bakkali, Abdellatif, Salomons, Gajja S., Somervaille, Tim C. P.
Vydáno v Leukemia (2016)

IDH1-mutated transgenic zebrafish lines: An in-vivo model for drug screening and functional analysis

Autor Gao, Ya, de Wit, Maurice, Struys, Eduard A., van der Linde, Herma C. Z., Salomons, Gajja S., Lamfers, Martine L. M., Willemsen, Rob, Sillevis Smitt, Peter A. E., French, Pim J.
Vydáno v PLoS One (2018)

A Phase Ib Clinical Trial of Metformin and Chloroquine in Patients with IDH1-Mutated Solid Tumors

Autor Khurshed, Mohammed, Molenaar, Remco J., van Linde, Myra E., Mathôt, Ron A., Struys, Eduard A., van Wezel, Tom, van Noorden, Cornelis J. F., Klümpen, Heinz-Josef, Bovée, Judith V. M. G., Wilmink, Johanna W.
Vydáno v Cancers (Basel) (2021)

In vivo efficacy of mutant IDH1 inhibitor HMS-101 and structural resolution of distinct binding site

Autor Chaturvedi, Anuhar, Goparaju, Ramya, Gupta, Charu, Weder, Julia, Klünemann, Thomas, Araujo Cruz, Michelle Maria, Kloos, Arnold, Goerlich, Kerstin, Schottmann, Renate, Othman, Basem, Struys, Eduard A., Bähre, Heike, Grote-Koska, Denis, Brand, Korbinian, Ganser, Arnold, Preller, Matthias, Heuser, Michael
Vydáno v Leukemia (2019)

Enantiomer-specific and paracrine leukemogenicity of mutant IDH metabolite 2-hydroxyglutarate

Autor Chaturvedi, Anuhar, Araujo Cruz, Michelle Maria, Jyotsana, Nidhi, Sharma, Amit, Goparaju, Ramya, Schwarzer, Adrian, Görlich, Kerstin, Schottmann, Renate, Struys, Eduard A., Jansen, Erwin E., Rohde, Christian, Müller-Tidow, Carsten, Geffers, Robert, Göhring, Gudrun, Ganser, Arnold, Thol, Felicitas, Heuser, Michael
Vydáno v Leukemia (2016)

TM-04 A TRANSGENIC ZEBRAFISH MODEL FOR GLIOMAS WITH MUTATIONS IN ISOCITRATE DEHYDROGENASE 1

Autor Gao, Ya D., van der Linde, Herma C. Z., Struys, Eduard A., van Breugel, Valeska, de Wit, Maurice, Erdem, Lale, Bovée, Judith V.M.G., Lamfers, Martine L. M., Silleviss Smitt, Peter A.E., Salomons, Gajja S., Willemsen, Rob, French, Pim J.
Vydáno v Neuro Oncol (2014)

D‐2‐hydroxyglutaric aciduria Type I: Functional analysis of D2HGDH missense variants

Autor Pop, Ana, Struys, Eduard A., Jansen, Erwin E. W., Fernandez, Matilde R., Kanhai, Warsha A., van Dooren, Silvy J. M., Ozturk, Senay, van Oostendorp, Justin, Lennertz, Pascal, Kranendijk, Martijn, van der Knaap, Marjo S., Gibson, K. Michael, van Schaftingen, Emile, Salomons, Gajja S.
Vydáno v Hum Mutat (2019)

Inhibition of mutant IDH1 decreases D-2-HG levels without affecting tumorigenic properties of chondrosarcoma cell lines

Autor Suijker, Johnny, Oosting, Jan, Koornneef, Annemarie, Struys, Eduard A., Salomons, Gajja S., Schaap, Frank G., Waaijer, Cathelijn J.F., Wijers-Koster, Pauline M., Briaire-de Bruijn, Inge H., Haazen, Lizette, Riester, Scott M., Dudakovic, Amel, Danen, Erik, Cleton-Jansen, Anne-Marie, van Wijnen, Andre J., Bovée, Judith V.M.G.
Vydáno v Oncotarget (2015)