HDQ, a Potent Inhibitor of Plasmodium falciparum Proliferation, Binds to the Quinone Reduction Site of the Cytochrome bc(1) Complex

Por Vallières, Cindy, Fisher, Nicholas, Antoine, Thomas, Al-Helal, Mohammed, Stocks, Paul, Berry, Neil G., Lawrenson, Alexandre S., Ward, Stephen A., O'Neill, Paul M., Biagini, Giancarlo A., Meunier, Brigitte
Publicado em 2012

The Molecular Basis of Folate Salvage in Plasmodium falciparum: CHARACTERIZATION OF TWO FOLATE TRANSPORTERS

Por Salcedo-Sora, J. Enrique, Ochong, Edwin, Beveridge, Susan, Johnson, David, Nzila, Alexis, Biagini, Giancarlo A., Stocks, Paul A., O'Neill, Paul M., Krishna, Sanjeev, Bray, Patrick G., Ward, Stephen A.
Publicado em 2011

Glutathione Transport: A New Role for PfCRT in Chloroquine Resistance

Por Patzewitz, Eva-Maria, Salcedo-Sora, J. Enrique, Wong, Eleanor H., Sethia, Sonal, Stocks, Paul A., Maughan, Spencer C., Murray, James A.H., Krishna, Sanjeev, Bray, Patrick G., Ward, Stephen A., Müller, Sylke
Publicado em 2013

PfCRT and the trans-vacuolar proton electrochemical gradient: regulating the access of chloroquine to ferriprotoporphyrin IX

Por Bray, Patrick G., Mungthin, Mathirut, Hastings, Ian M., Biagini, Giancarlo A., Saidu, Dauda K., Lakshmanan, Viswanathan, Johnson, David J., Hughes, Ruth H., Stocks, Paul A., O'Neill, Paul M., Fidock, David A., Warhurst, David C., Ward, Stephen A.
Publicado em 2006

A novel drug for uncomplicated malaria: targeted high throughput screening (HTS) against the type II NADH:ubiquinone oxidoreductase (PfNdh2) of Plasmodium falciparum

Por Ward, Steve A, Fisher, Nicholas, Hill, Alasdair, Mbekeani, Alison, Shone, Alison, Nixon, Gemma, Stocks, Paul, Gibbons, Peter, Amewu, Richard, Hong, David W, Barton, Victoria, Pidathala, Chandra, Chadwick, James, Le Pensee, Louise, Warman, Ashley, Sharma, Raman, Berry, Neil G, O'Neill, Paul M, Biagini, Giancarlo A
Publicado em 2010

Development of a novel drug for uncomplicated malaria targeting the mitochondrial NADH:quinone oxidoreductase

Por Biagini, Giancarlo A, Hill, Alasdair, Mbekeani, Alison, Shone, Alison, Nixon, Gemma, Stocks, Paul, Gibbons, Peter, Amewu, Richard, Hong, David W, Barton, Victoria, Pidathala, Chandra, Chadwick, James, Le Pensee, Louise, Warman, Ashley, Sharma, Raman, Fisher, Nick, Berry, Neil G, O'Neill, Paul M, Ward, Steve A
Publicado em 2010

Identification of Novel Antimalarial Chemotypes via Chemoinformatic Compound Selection Methods for a High-Throughput Screening Program against the Novel Malarial Target, PfNDH2: In...

Por Sharma, Raman, Lawrenson, Alexandre S., Fisher, Nicholas E., Warman, Ashley J., Shone, Alison E., Hill, Alasdair, Mbekeani, Alison, Pidathala, Chandrakala, Amewu, Richard K., Leung, Suet, Gibbons, Peter, Hong, David W., Stocks, Paul, Nixon, Gemma L., Chadwick, James, Shearer, Joanne, Gowers, Ian, Cronk, David, Parel, Serge P., O'Neill, Paul M., Ward, Stephen A., Biagini, Giancarlo A., Berry, Neil G.
Publicado em 2012

Identification, Design and Biological Evaluation of Bisaryl Quinolones Targeting Plasmodium falciparum Type II NADH:Quinone Oxidoreductase (PfNDH2)

Por Pidathala, Chandrakala, Amewu, Richard, Pacorel, Bénédicte, Nixon, Gemma L., Gibbons, Peter, Hong, W. David, Leung, Suet C., Berry, Neil G., Sharma, Raman, Stocks, Paul A., Srivastava, Abhishek, Shone, Alison E., Charoensutthivarakul, Sitthivut, Taylor, Lee, Berger, Olivier, Mbekeani, Alison, Hill, Alasdair, Fisher, Nicholas E., Warman, Ashley J., Biagini, Giancarlo A., Ward, Stephen A., O’Neill, Paul M.
Publicado em 2012

Identification, Design and Biological Evaluation of Heterocyclic Quinolones Targeting Plasmodium falciparum Type II NADH:Quinone Oxidoreductase (PfNDH2)

Por Leung, Suet C., Gibbons, Peter, Amewu, Richard, Nixon, Gemma L., Pidathala, Chandrakala, Hong, W. David, Pacorel, Bénédicte, Berry, Neil G., Sharma, Raman, Stocks, Paul A., Srivastava, Abhishek, Shone, Alison E., Charoensutthivarakul, Sitthivut, Taylor, Lee, Berger, Olivier, Mbekeani, Alison, Hill, Alasdair, Fisher, Nicholas E., Warman, Ashley J., Biagini, Giancarlo A., Ward, Stephen A., O’Neill, Paul M.
Publicado em 2012

Generation of quinolone antimalarials targeting the Plasmodium falciparum mitochondrial respiratory chain for the treatment and prophylaxis of malaria

Por Biagini, Giancarlo A., Fisher, Nicholas, Shone, Alison E., Mubaraki, Murad A., Srivastava, Abhishek, Hill, Alisdair, Antoine, Thomas, Warman, Ashley J., Davies, Jill, Pidathala, Chandrakala, Amewu, Richard K., Leung, Suet C., Sharma, Raman, Gibbons, Peter, Hong, David W., Pacorel, Bénédicte, Lawrenson, Alexandre S., Charoensutthivarakul, Sitthivut, Taylor, Lee, Berger, Olivier, Mbekeani, Alison, Stocks, Paul A., Nixon, Gemma L., Chadwick, James, Hemingway, Janet, Delves, Michael J., Sinden, Robert E., Zeeman, Anne-Marie, Kocken, Clemens H. M., Berry, Neil G., O’Neill, Paul M., Ward, Stephen A.
Publicado em 2012