The Molecular Basis of Folate Salvage in Plasmodium falciparum: CHARACTERIZATION OF TWO FOLATE TRANSPORTERS

Tetrahydrofolates are essential cofactors for DNA synthesis and methionine metabolism. Malaria parasites are capable both of synthesizing tetrahydrofolates and precursors de novo and of salvaging them from the environment. The biosynthetic route has been studied in some detail over decades, whereas...

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Detalhes bibliográficos
Main Authors: Salcedo-Sora, J. Enrique, Ochong, Edwin, Beveridge, Susan, Johnson, David, Nzila, Alexis, Biagini, Giancarlo A., Stocks, Paul A., O'Neill, Paul M., Krishna, Sanjeev, Bray, Patrick G., Ward, Stephen A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Metabolism
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3247980/
https://ncbi.nlm.nih.gov/pubmed/21998306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.286054
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