The Molecular Basis of Folate Salvage in Plasmodium falciparum: CHARACTERIZATION OF TWO FOLATE TRANSPORTERS

Tetrahydrofolates are essential cofactors for DNA synthesis and methionine metabolism. Malaria parasites are capable both of synthesizing tetrahydrofolates and precursors de novo and of salvaging them from the environment. The biosynthetic route has been studied in some detail over decades, whereas...

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Autori principali: Salcedo-Sora, J. Enrique, Ochong, Edwin, Beveridge, Susan, Johnson, David, Nzila, Alexis, Biagini, Giancarlo A., Stocks, Paul A., O'Neill, Paul M., Krishna, Sanjeev, Bray, Patrick G., Ward, Stephen A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2011
Soggetti:
Metabolism
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3247980/
https://ncbi.nlm.nih.gov/pubmed/21998306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.286054
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