PfCRT and the trans-vacuolar proton electrochemical gradient: regulating the access of chloroquine to ferriprotoporphyrin IX

It is accepted that resistance of Plasmodium falciparum to chloroquine (CQ) is caused primarily by mutations in the pfcrt gene. However, a consensus has not yet been reached on the mechanism by which resistance is achieved. CQ-resistant (CQR) parasite lines accumulate less CQ than do CQ-sensitive (C...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Bray, Patrick G., Mungthin, Mathirut, Hastings, Ian M., Biagini, Giancarlo A., Saidu, Dauda K., Lakshmanan, Viswanathan, Johnson, David J., Hughes, Ruth H., Stocks, Paul A., O'Neill, Paul M., Fidock, David A., Warhurst, David C., Ward, Stephen A.
Формат: Artigo
Язык:Inglês
Опубликовано: 2006
Предметы:
Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2943415/
https://ncbi.nlm.nih.gov/pubmed/16956382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2006.05368.x
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы