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Differences in trans-stimulated chloroquine efflux kinetics are linked to PfCRT in Plasmodium falciparum

The mechanism underpinning chloroquine drug resistance in the human malarial parasite Plasmodium falciparum has remained controversial. Currently discussed models include a carrier or a channel for chloroquine, the former actively expelling the drug, the latter facilitating its passive diffusion, ou...

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מידע ביבליוגרפי
Main Authors: Sanchez, Cecilia P., Rohrbach, Petra, McLean, Jeremy E., Fidock, David A., Stein, Wilfred D., Lanzer, Michael
פורמט: Artigo
שפה:Inglês
יצא לאור: 2007
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944662/
https://ncbi.nlm.nih.gov/pubmed/17493125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2007.05664.x
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