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Differences in trans-stimulated chloroquine efflux kinetics are linked to PfCRT in Plasmodium falciparum

The mechanism underpinning chloroquine drug resistance in the human malarial parasite Plasmodium falciparum has remained controversial. Currently discussed models include a carrier or a channel for chloroquine, the former actively expelling the drug, the latter facilitating its passive diffusion, ou...

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Bibliografische gegevens
Hoofdauteurs: Sanchez, Cecilia P., Rohrbach, Petra, McLean, Jeremy E., Fidock, David A., Stein, Wilfred D., Lanzer, Michael
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2007
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944662/
https://ncbi.nlm.nih.gov/pubmed/17493125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2007.05664.x
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