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Differences in trans-stimulated chloroquine efflux kinetics are linked to PfCRT in Plasmodium falciparum

The mechanism underpinning chloroquine drug resistance in the human malarial parasite Plasmodium falciparum has remained controversial. Currently discussed models include a carrier or a channel for chloroquine, the former actively expelling the drug, the latter facilitating its passive diffusion, ou...

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Detalhes bibliográficos
Main Authors: Sanchez, Cecilia P., Rohrbach, Petra, McLean, Jeremy E., Fidock, David A., Stein, Wilfred D., Lanzer, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944662/
https://ncbi.nlm.nih.gov/pubmed/17493125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2007.05664.x
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