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Chlorpheniramine Analogues Reverse Chloroquine Resistance in Plasmodium falciparum by Inhibiting PfCRT
[Image: see text] The emergence and spread of malaria parasites that are resistant to chloroquine (CQ) has been a disaster for world health. The antihistamine chlorpheniramine (CP) partially resensitizes CQ-resistant (CQR) parasites to CQ but possesses little intrinsic antiplasmodial activity. Mutat...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Chemical
Society
2014
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| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4027738/ https://ncbi.nlm.nih.gov/pubmed/24900883 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml5000228 |
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