Single and Multiple Gene Manipulations in Mouse Models of Human Cancer

Por Lehman, Heather L, Stairs, Douglas B
Publicado no Cancer Growth Metastasis (2015)

ANIMAL MODELS OF CANCER BIOLOGY

Por Yee, Nelson S., Ignatenko, Natalia, Finnberg, Niklas, Lee, Nikki, Stairs, Douglas
Publicado no Cancer Growth Metastasis (2015)

Barrett's Esophagus: Emerging Knowledge and Management Strategies

Por Bhardwaj, Atul, Stairs, Douglas B., Mani, Haresh, McGarrity, Thomas J.
Publicado em 2012

p120-Catenin Down-Regulation and Epidermal Growth Factor Receptor Overexpression Results in a Transformed Epithelium That Mimics Esophageal Squamous Cell Carcinoma

Por Lehman, Heather L., Yang, Xuebin, Welsh, Patricia A., Stairs, Douglas B.
Publicado no Am J Pathol (2015)

NFkB hyperactivation causes invasion of esophageal squamous cell carcinoma with EGFR overexpression and p120-catenin down-regulation

Por Lehman, Heather L., Kidacki, Michal, Warrick, Joshua I., Stairs, Douglas B.
Publicado no Oncotarget (2018)

Cox2 and β-Catenin/T-cell Factor Signaling Intestinalize Human Esophageal Keratinocytes When Cultured under Organotypic Conditions

Por Kong, Jianping, Crissey, Mary Ann S, Stairs, Douglas B, Sepulveda, Antonia R, Lynch, John P
Publicado em 2011

Autocrine prolactin induced by the Pten–Akt pathway is required for lactation initiation and provides a direct link between the Akt and Stat5 pathways

Por Chen, Chien-Chung, Stairs, Douglas B., Boxer, Robert B., Belka, George K., Horseman, Nelson D., Alvarez, James V., Chodosh, Lewis A.
Publicado em 2012

Cdx1 and c-Myc Foster the Initiation of Transdifferentiation of the Normal Esophageal Squamous Epithelium toward Barrett's Esophagus

Por Stairs, Douglas B., Nakagawa, Hiroshi, Klein-Szanto, Andres, Mitchell, Shukriyyah D., Silberg, Debra G., Tobias, John W., Lynch, John P., Rustgi, Anil K.
Publicado em 2008

Akt is required for Stat5 activation and mammary differentiation

Por Chen, Chien-Chung, Boxer, Robert B, Stairs, Douglas B, Portocarrero, Carla P, Horton, Rachel H, Alvarez, James V, Birnbaum, Morris J, Chodosh, Lewis A
Publicado em 2010

Increasing diagnostic accuracy to grade dysplasia in Barrett’s esophagus using an immunohistochemical panel for CDX2, p120ctn, c-Myc and Jagged1

Por Karamchandani, Dipti M., Lehman, Heather L., Ohanessian, Sara E., Massé, Julie, Welsh, Patricia A., Odze, Robert D., Goldblum, John R., Berg, Arthur S., Stairs, Douglas B.
Publicado no Diagn Pathol (2016)

A subpopulation of mouse esophageal basal cells has properties of stem cells with the capacity for self-renewal and lineage specification

Por Kalabis, Jiri, Oyama, Kenji, Okawa, Takaomi, Nakagawa, Hiroshi, Michaylira, Carmen Z., Stairs, Douglas B., Figueiredo, Jose-Luiz, Mahmood, Umar, Diehl, J. Alan, Herlyn, Meenhard, Rustgi, Anil K.
Publicado em 2008

Inhibition of Notch signaling enhances transdifferentiation of the esophageal squamous epithelium towards a Barrett's-like metaplasia via KLF4

Por Vega, Maria E, Giroux, Véronique, Natsuizaka, Mitsuteru, Liu, Mingen, Klein-Szanto, Andres J, Stairs, Douglas B, Nakagawa, Hiroshi, Wang, Kenneth K, Wang, Timothy C, Lynch, John P, Rustgi, Anil K
Publicado no Cell Cycle (2015)

The functional interplay between EGFR overexpression, hTERT activation, and p53 mutation in esophageal epithelial cells with activation of stromal fibroblasts induces tumor develop...

Por Okawa, Takaomi, Michaylira, Carmen Z., Kalabis, Jiri, Stairs, Douglas B., Nakagawa, Hiroshi, Andl, Claudia, Johnstone, Cameron N., Klein-Szanto, Andres J., El-Deiry, Wafik S., Cukierman, Edna, Herlyn, Meenhard, Rustgi, Anil K.
Publicado em 2007

IGFBP-3 Regulates Esophageal Tumor Growth Through IGF-Dependent and Independent Mechanisms

Por Takaoka, Munenori, Kim, Seok-Hyun, Okawa, Takaomi, Michaylira, Carmen Z., Stairs, Douglas B., Johnstone, Cameron N., Andl, Claudia D., Rhoades, Ben, Lee, James J., Klein-Szanto, Andres J.P., El-Deiry, Wafik S., Nakagawa, Hiroshi
Publicado em 2007

Deletion of p120-catenin results in a tumor microenvironment with inflammation and cancer that establishes it as a tumor suppressor gene

Por Stairs, Douglas B., Bayne, Lauren J., Rhoades, Ben, Vega, Maria E., Waldron, Todd J., Kalabis, Jiri, Klein-Szanto, Andres, Lee, Ju-Seog, Katz, Jonathan P., Diehl, J. Alan, Reynolds, Albert B., Vonderheide, Robert H., Rustgi, Anil K.
Publicado em 2011

EGFR and mutant p53 expand esophageal cellular subpopulation capable of epithelial-to-mesenchymal transition through ZEB transcription factors

Por Ohashi, Shinya, Natsuizaka, Mitsuteru, Wong, Gabrielle S., Michaylira, Carmen Z., Grugan, Katharine D., Stairs, Douglas B., Kalabis, Jiri, Vega, Maria E., Kalman, Ross A., Nakagawa, Momo, Klein-Szanto, Andres J, Herlyn, Meenhard, Diehl, J. Alan, Rustgi, Anil K., Nakagawa, Hiroshi
Publicado em 2010

SOX2 Is an Amplified Lineage Survival Oncogene in Lung and Esophageal Squamous Cell Carcinomas

Por Bass, Adam J., Watanabe, Hideo, Mermel, Craig H., Yu, Soyoung, Perner, Sven, Verhaak, Roel G., Kim, So Young, Wardwell, Leslie, Tamayo, Pablo, Gat-Viks, Irit, Ramos, Alex H., Woo, Michele S., Weir, Barbara A., Getz, Gad, Beroukhim, Rameen, O’Kelly, Michael, Dutt, Amit, Rozenblatt-Rosen, Orit, Dziunycz, Piotr, Komisarof, Justin, Chirieac, Lucian R., LaFargue, Christopher J., Scheble, Veit, Wilbertz, Theresia, Ma, Changqing, Rao, Shilpa, Nakagawa, Hiroshi, Stairs, Douglas B., Lin, Lin, Giordano, Thomas J., Wagner, Patrick, Minna, John D., Gazdar, Adi F., Zhu, Chang Qi, Brose, Marcia S., Cecconello, Ivan, Ribeiro, Ulysses, Marie, Suely K., Dahl, Olav, Shivdasani, Ramesh A., Tsao, Ming-Sound, Rubin, Mark A., Wong, Kwok K., Regev, Aviv, Hahn, William C., Beer, David G., Rustgi, Anil K., Meyerson, Matthew
Publicado em 2009