Inhibition of Notch signaling enhances transdifferentiation of the esophageal squamous epithelium towards a Barrett's-like metaplasia via KLF4

Barrett's esophagus (BE) is defined as an incomplete intestinal metaplasia characterized generally by the presence of columnar and goblet cells in the formerly stratified squamous epithelium of the esophagus. BE is known as a precursor for esophageal adenocarcinoma. Currently, the cell of origi...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Cycle
Prif Awduron: Vega, Maria E, Giroux, Véronique, Natsuizaka, Mitsuteru, Liu, Mingen, Klein-Szanto, Andres J, Stairs, Douglas B, Nakagawa, Hiroshi, Wang, Kenneth K, Wang, Timothy C, Lynch, John P, Rustgi, Anil K
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Taylor & Francis 2015
Pynciau:
Report
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4614677/
https://ncbi.nlm.nih.gov/pubmed/25558829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15384101.2014.972875
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