Inhibition of Notch signaling enhances transdifferentiation of the esophageal squamous epithelium towards a Barrett's-like metaplasia via KLF4

Barrett's esophagus (BE) is defined as an incomplete intestinal metaplasia characterized generally by the presence of columnar and goblet cells in the formerly stratified squamous epithelium of the esophagus. BE is known as a precursor for esophageal adenocarcinoma. Currently, the cell of origi...

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Bibliografiske detaljer
Udgivet i:Cell Cycle
Main Authors: Vega, Maria E, Giroux, Véronique, Natsuizaka, Mitsuteru, Liu, Mingen, Klein-Szanto, Andres J, Stairs, Douglas B, Nakagawa, Hiroshi, Wang, Kenneth K, Wang, Timothy C, Lynch, John P, Rustgi, Anil K
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2015
Fag:
Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4614677/
https://ncbi.nlm.nih.gov/pubmed/25558829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15384101.2014.972875
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