Inhibition of Notch signaling enhances transdifferentiation of the esophageal squamous epithelium towards a Barrett's-like metaplasia via KLF4

Barrett's esophagus (BE) is defined as an incomplete intestinal metaplasia characterized generally by the presence of columnar and goblet cells in the formerly stratified squamous epithelium of the esophagus. BE is known as a precursor for esophageal adenocarcinoma. Currently, the cell of origi...

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Detalhes bibliográficos
Publicado no:Cell Cycle
Main Authors: Vega, Maria E, Giroux, Véronique, Natsuizaka, Mitsuteru, Liu, Mingen, Klein-Szanto, Andres J, Stairs, Douglas B, Nakagawa, Hiroshi, Wang, Kenneth K, Wang, Timothy C, Lynch, John P, Rustgi, Anil K
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
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Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4614677/
https://ncbi.nlm.nih.gov/pubmed/25558829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15384101.2014.972875
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